Yilmaz Süreyya, Topcu Fusun, Selimoglu Sen Hadice, Yildirim Yasar, Yilmaz Zülfükar, Kara Ali Veysel, Akgul Ozmen Cihan
Department of Chest Diseases, Faculty of Medicine, Dicle University, 21100 Diyarbakir, Turkey.
Department of Internal Medicine, Faculty of Medicine, Dicle University, 21100 Diyarbakir, Turkey.
Case Rep Pulmonol. 2015;2015:249612. doi: 10.1155/2015/249612. Epub 2015 Mar 22.
Antiphospholipid syndrome (APS) is an autoimmune disease characterised by arterial and/or venous thrombosis and/or recurrent pregnancy loss in the presence of antiphospholipid (APL) antibodies. It is evaluated as APS when it develops associated with other systemic autoimmune diseases or primary APS if there is no concomitant disorder. In this study, we present a case of a 16-year-old male patient with primary APS. The patient was admitted with presumptive diagnosis of pneumonia, but multiple pulmonary thromboembolism (PTE) was observed on computerized tomography (CT) pulmonary angiography. APL antibodies positivity and thrombocytopenia developed in our patient. The patient was evaluated as primary APS since another etiology that could explain PTE was not found. Primary APS is a rare disease in children along with adolescents, compared with APS associated with other systemic autoimmune diseases. We present here a young male patient with primary APS and PTE to contribute to the literature. The patient initially had pneumonia but later developed PTE and thrombocytopenia.
抗磷脂综合征（APS）是一种自身免疫性疾病，其特征为在存在抗磷脂（APL）抗体的情况下发生动脉和/或静脉血栓形成和/或反复流产。当它与其他系统性自身免疫性疾病相关联时被评估为APS，如果没有伴随疾病则为原发性APS。在本研究中，我们报告一例16岁男性原发性APS患者。该患者因疑似肺炎入院，但在计算机断层扫描（CT）肺血管造影中观察到多发肺血栓栓塞症（PTE）。我们的患者出现了APL抗体阳性和血小板减少症。由于未发现其他可解释PTE的病因，该患者被评估为原发性APS。与与其他系统性自身免疫性疾病相关的APS相比，原发性APS在儿童和青少年中是一种罕见疾病。我们在此展示一名患有原发性APS和PTE的年轻男性患者，以丰富相关文献。该患者最初患有肺炎，但后来发展为PTE和血小板减少症。
