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既往存在的影像学骨关节炎对转子间骨折后功能结局的影响。

The influence of pre-existing radiographic osteoarthritis on functional outcome after trochanteric fracture.

作者信息

Boese Christoph Kolja, Buecking Benjamin, Schwarting Tim, Debus Florian, Ruchholtz Steffen, Bliemel Christoph, Frink Michael, Lechler Philipp

机构信息

Department of Orthopaedic and Trauma Surgery, University Hospital of Cologne, Cologne, Germany.

出版信息

Int Orthop. 2015 Jul;39(7):1405-10. doi: 10.1007/s00264-014-2663-9. Epub 2015 Jan 21.

Abstract

PURPOSE

It is crucially important to optimise functional outcome after fixation of trochanteric femoral fractures. While a number of risk factors that predict a poor clinical course have been identified, the influence of pre-existing radiographic osteoarthritis (OA) of the hip is unclear.

METHODS

The influence of pre-existing radiographic OA of the hip on short- to mid-term functional outcome was prospectively analysed in a cohort of patients undergoing proximal femoral nailing for trochanteric fracture. OA was graded according to Kellgren and Lawrence; functional outcome was assessed at six and 12 months by the Harris hip score (HHS), the timed up and go (TUG) test and the Barthel Index.

RESULTS

Our cohort comprised 188 patients (58 were male and 130 female), with a mean age of 82 years. At six and 12 months postoperatively, the HHS (p < 0.001 and p = 0.008, respectively) and Barthel Index (p < 0.001 and p = 0.02, respectively) correlated significantly with the grade of pre-existing OA. After adjustment for confounding variables, there was a significant association between the grade of pre-existing OA and the HHS at six months (p = 0.02). Although we observed trends suggestive of other relationships, none reached statistical significance.

CONCLUSIONS

Pre-existing radiographic OA of the hip is an important determinant of clinical outcome in elderly patients with a trochanteric femoral fracture. Further studies will be needed to establish the most effective means of restoring hip function after trochanteric femoral fracture in patients with radiographic OA of the hip.

摘要

目的

优化股骨转子间骨折固定术后的功能结局至关重要。虽然已确定了一些预测临床过程不佳的风险因素,但髋部术前存在的影像学骨关节炎(OA)的影响尚不清楚。

方法

对一组接受股骨近端髓内钉治疗转子间骨折的患者进行前瞻性分析,以探讨髋部术前存在的影像学OA对短期至中期功能结局的影响。OA根据Kellgren和Lawrence分级;在6个月和12个月时通过Harris髋关节评分(HHS)、计时起立行走(TUG)测试和Barthel指数评估功能结局。

结果

我们的队列包括188例患者(58例男性和130例女性),平均年龄82岁。术后6个月和12个月时,HHS(分别为p < 0.001和p = 0.008)和Barthel指数(分别为p < 0.001和p = 0.02)与术前OA分级显著相关。在对混杂变量进行调整后,术前OA分级与6个月时的HHS之间存在显著关联(p = 0.02)。尽管我们观察到了其他关系的趋势,但均未达到统计学意义。

结论

髋部术前存在的影像学OA是老年股骨转子间骨折患者临床结局的重要决定因素。需要进一步研究以确定在髋部有影像学OA的患者中,股骨转子间骨折后恢复髋关节功能的最有效方法。

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