Feinstein A, DeLuca J, Baune B T, Filippi M, Lassman H
University of Toronto, Department of Psychiatry and Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada M5R 3B6.
Kessler Foundation Research Center, West Orange, New Jersey, USA.
Mult Scler Relat Disord. 2013 Jan;2(1):4-12. doi: 10.1016/j.msard.2012.08.001. Epub 2012 Sep 25.
Multiple sclerosis is associated with a wide array of behavioral problems. This brief overview begins with a summary of the pathophysiology and treatment of MS. Thereafter, sections are devoted to psychiatric syndromes and cognitive decline linked to MS. The immune basis and brain imaging data associated with these changes are subsequently reviewed. The frequency and severity of these changes in mentation highlight the point that MS patients should, as part of their routine care, have access to psychiatrists, neuropsychologists and allied mental health specialists.
多发性硬化症与一系列行为问题相关。本简要概述首先总结多发性硬化症的病理生理学和治疗方法。此后，各部分将专门讨论与多发性硬化症相关的精神综合征和认知衰退。随后将回顾与这些变化相关的免疫基础和脑成像数据。这些思维变化的频率和严重程度突出了一点，即作为常规护理的一部分，多发性硬化症患者应能接触到精神科医生、神经心理学家和相关心理健康专家。
