MS 相关的神经精神方面及其心理治疗与性功能障碍：范围综述。
Sexual dysfunctions in MS in relation to neuropsychiatric aspects and its psychological treatment: A scoping review.
机构信息
Institut für Neuroimmunologie und Multiple Sklerose, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Klinik und Poliklinik für Neurologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
出版信息
PLoS One. 2018 Feb 27;13(2):e0193381. doi: 10.1371/journal.pone.0193381. eCollection 2018.
OBJECTIVE
Sexual dysfunction in multiple sclerosis (MS) is a significant, but often underestimated and overlooked suffering. Interventions to treat sexual dysfunction in MS are rare. The relation between sexual dysfunction in MS and psychological as well as neuropsychological aspects is evident. However, this field of research remains markedly underdeveloped in this severe chronic illness. The aim of this scoping review is to describe the relevant knowledge in this area and to identify psychological interventions to treat sexual dysfunctions in MS.
METHODS
A scoping review was conducted to answer the following questions: (1) Which psychological and neuropsychological factors impact on sexual dysfunction in MS and vice versa? (2) What kind of psychological interventions aiming to improve sexual dysfunctions in MS are available? A comprehensive search and review of MEDLINE, PsycINFO, and CINAHL was completed by using a recent methodological framework for scoping reviews.
RESULTS
23 publications covering a total of 13,259 people with MS and 532 healthy controls were identified. Sexual dysfunction was found to be very common in MS and there is an obvious relation to psychological disorders as e.g. depression and anxiety and also to psychological aspects as partner relationship and quality of life. The relation between sexual dysfunction in MS and neuropsychological impairment has only rarely been studied and no clear results were found. Only two studies were identified, assessing the effectiveness of psychological intervention studies on sexual dysfunction in people with MS, and a third study presenting a secondary analysis of a study targeting depression. All three studies reported significant improvements in sexual dysfunction as well as partly in psychological variables.
CONCLUSIONS
There is a pressing need for the development and adequate evaluation of psychological interventions for sexual dysfunctions in MS. In addition, sexual dysfunction and its impact on psychological wellbeing should be more focussed in clinical care.
REGISTRATION
This review is registered with PROSPERO; Registration number: CRD42016033066.
目的
多发性硬化症（MS）患者的性功能障碍是一种严重但常常被低估和忽视的痛苦。针对 MS 患者性功能障碍的干预措施非常少见。MS 患者的性功能障碍与心理和神经心理学方面有明显的关系。然而，在这种严重的慢性疾病中，这一研究领域的发展明显不足。本综述的目的是描述该领域的相关知识，并确定治疗 MS 患者性功能障碍的心理干预措施。
方法
进行了范围综述，以回答以下问题：（1）哪些心理和神经心理学因素会影响 MS 患者的性功能障碍，反之亦然？（2）有哪些旨在改善 MS 患者性功能障碍的心理干预措施？使用最近的范围综述方法框架，对 MEDLINE、PsycINFO 和 CINAHL 进行了全面的搜索和综述。
结果
确定了 23 篇文献，共涵盖了 13259 名 MS 患者和 532 名健康对照者。MS 患者的性功能障碍非常常见，与心理障碍（如抑郁和焦虑）以及伴侣关系和生活质量等心理方面有明显的关系。MS 患者的性功能障碍与神经心理损伤之间的关系仅很少被研究，没有明确的结果。仅确定了两项研究，评估了针对 MS 患者性功能障碍的心理干预研究的有效性，以及第三项研究报告了一项针对抑郁的研究的二次分析。这三项研究均报告了性功能障碍以及部分心理变量的显著改善。
结论
迫切需要开发和充分评估针对 MS 患者性功能障碍的心理干预措施。此外，应该更加关注性功能障碍及其对心理健康的影响在临床护理中的作用。
登记
本综述在 PROSPERO 上进行了登记；注册号：CRD42016033066。
Zotero 插件