van Schayck C P, van Weel C, Folgering H, Verbeek A L, van Herwaarden C L
Department of General Practice/Family Medicine, Nijmegen University, The Netherlands.
Scand J Prim Health Care. 1989 Oct;7(3):137-42. doi: 10.3109/02813438909087230.
The study comprised 223 patients with airflow obstruction and/or bronchial hyperreactivity from 29 general practices in the catchment area of Nijmegen University. Fifty-six patients were treated by 19 chest physicians, the remaining 167 by their general practitioners (GPs), without specialist care. The specialists treated more allergic patients than the GP (p less than 0.05). No other relevant differences in sex, age, smoking behaviour, and severity of the disease (symptoms, lung function, and bronchial hyperreactivity) could be observed between these two groups of patients. Chest physicians prescribed almost three times as many drugs as GPs. No immediate response to the prescribed bronchodilators was found in 16% of the patients treated by the GPs, nor in 20% of the patients treated by the specialists. We could identify only a weak relationship between the severity of the disease (symptoms and pulmonary function combined) and the prescribed pharmacotherapy: with growing degrees of severity the GP seems to prescribe more bronchodilators, the specialist more inhaled corticosteroids. Prescribed pharmacotherapy should be based on the combination of symptoms, pulmonary function, bronchial hyperreactivity, and reversibility on the prescribed bronchodilators.
该研究纳入了奈梅亨大学集水区29家普通诊所的223例气流受限和/或支气管高反应性患者。56例患者由19名胸科医生治疗,其余167例由他们的全科医生(GP)治疗,未接受专科护理。专科医生治疗的过敏患者比全科医生多(p小于0.05)。在这两组患者之间,未观察到性别、年龄、吸烟行为和疾病严重程度(症状、肺功能和支气管高反应性)的其他相关差异。胸科医生开出的药物几乎是全科医生的三倍。在全科医生治疗的患者中,16%的患者对开具的支气管扩张剂没有立即反应,专科医生治疗的患者中这一比例为20%。我们只能确定疾病严重程度(症状和肺功能综合)与开具的药物治疗之间存在微弱的关系:随着严重程度的增加,全科医生似乎开出更多的支气管扩张剂,专科医生开出更多的吸入性糖皮质激素。开具的药物治疗应基于症状、肺功能、支气管高反应性以及对开具的支气管扩张剂的反应性。