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埃塞俄比亚未被发现的艾滋病毒呈阳性儿童。

The missed HIV-positive children of Ethiopia.

作者信息

Pegurri Elisabetta, Konings Elke, Crandall Bud, Haile-Selassie Hiwot, Matinhure Nelia, Naamara Warren, Assefa Yibeltal

机构信息

The Joint United Nations Programme on HIV/AIDS (UNAIDS), Addis Ababa, Ethiopia.

Management Sciences for Health (MSH), Addis Ababa, Ethiopia.

出版信息

PLoS One. 2015 Apr 16;10(4):e0124041. doi: 10.1371/journal.pone.0124041. eCollection 2015.

Abstract

OBJECTIVE

As elsewhere, due to scarcity of data and limited awareness of HIV infection, especially in older children, the HIV epidemic among Ethiopian children appears neglected in national programs (children ART coverage is of only 12% in 2013). This paper estimates the country burden of HIV in older children and investigates the prevalence of HIV in orphans and vulnerable children (OVC) households.

DESIGN/METHODS: We analyzed national HIV data for Ethiopia, using Spectrum/ Estimation and Projection Package (EPP) and primary data on children living in households with at least one HIV-positive adult in the Amhara and Tigrai regions. Descriptive analysis of the age and sex distribution of HIV-positive OVC in Ethiopia was performed.

RESULTS

Our Spectrum/EPP analysis estimated the population of HIV-positive children under 15 years old to be 160,000 in 2013. The majority of children (81•6%) were aged five to 14 years. The estimated number of orphans due to AIDS was 800,000. The empirical data from almost 10,000 OVC under 18 years showed 11•9% were HIV-positive, the majority of whom were between five and 10 years old with no significant difference between males and females.

CONCLUSIONS

There is a large population of children living with HIV in Ethiopia, the magnitude of which not previously recognized. The majority were vertically infected and never identified nor linked into treatment. OVC represent a reachable group which could account for a substantial proportion of the HIV infected older children. We recommend that HIV programs urgently synergize with social protection sectors and address these children with HIV testing and related services.

摘要

目的

与其他地方一样,由于数据匮乏以及对艾滋病毒感染的认识有限,尤其是在大龄儿童中,埃塞俄比亚儿童中的艾滋病毒疫情在国家项目中似乎被忽视了(2013年儿童抗逆转录病毒治疗覆盖率仅为12%)。本文估计了该国大龄儿童的艾滋病毒负担,并调查了孤儿和弱势儿童(OVC)家庭中的艾滋病毒流行情况。

设计/方法:我们使用Spectrum/估计与预测软件包(EPP)分析了埃塞俄比亚的国家艾滋病毒数据,以及阿姆哈拉和提格雷地区至少有一名艾滋病毒阳性成年人的家庭中儿童的原始数据。对埃塞俄比亚艾滋病毒阳性OVC的年龄和性别分布进行了描述性分析。

结果

我们的Spectrum/EPP分析估计,2013年15岁以下艾滋病毒阳性儿童人数为16万。大多数儿童(81.6%)年龄在5至14岁之间。因艾滋病成为孤儿的估计人数为80万。来自近10000名18岁以下OVC的实证数据显示,11.9%为艾滋病毒阳性,其中大多数年龄在5至10岁之间,男女之间无显著差异。

结论

埃塞俄比亚有大量感染艾滋病毒的儿童,其规模此前未被认识到。大多数是垂直感染,从未被识别或与治疗联系起来。OVC是一个可触及的群体,可能占感染艾滋病毒的大龄儿童的很大比例。我们建议艾滋病毒项目紧急与社会保护部门协同合作,通过艾滋病毒检测及相关服务来关注这些儿童。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/081b/4400141/ac86673f47d5/pone.0124041.g001.jpg

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