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在欧洲国家以下层面满足《国际卫生条例(2005)》监测核心能力要求:症状监测的附加价值

Meeting the International Health Regulations (2005) surveillance core capacity requirements at the subnational level in Europe: the added value of syndromic surveillance.

作者信息

Ziemann Alexandra, Rosenkötter Nicole, Riesgo Luis Garcia-Castrillo, Fischer Matthias, Krämer Alexander, Lippert Freddy K, Vergeiner Gernot, Brand Helmut, Krafft Thomas

机构信息

Department of International Health, School of Public Health and Primary Care (CAPHRI), Faculty of Health, Medicine and Life Sciences, Maastricht University, P.O. Box 616, 6200, MD, Maastricht, The Netherlands.

Department of Medical Sciences and Surgery, Faculty of Medicine, University of Cantabria, Avenida de los Castros s/n, 39005, Santander, Spain.

出版信息

BMC Public Health. 2015 Feb 7;15:107. doi: 10.1186/s12889-015-1421-2.

Abstract

BACKGROUND

The revised World Health Organization's International Health Regulations (2005) request a timely and all-hazard approach towards surveillance, especially at the subnational level. We discuss three questions of syndromic surveillance application in the European context for assessing public health emergencies of international concern: (i) can syndromic surveillance support countries, especially the subnational level, to meet the International Health Regulations (2005) core surveillance capacity requirements, (ii) are European syndromic surveillance systems comparable to enable cross-border surveillance, and (iii) at which administrative level should syndromic surveillance best be applied?

DISCUSSION

Despite the ongoing criticism on the usefulness of syndromic surveillance which is related to its clinically nonspecific output, we demonstrate that it was a suitable supplement for timely assessment of the impact of three different public health emergencies affecting Europe. Subnational syndromic surveillance analysis in some cases proved to be of advantage for detecting an event earlier compared to national level analysis. However, in many cases, syndromic surveillance did not detect local events with only a small number of cases. The European Commission envisions comparability of surveillance output to enable cross-border surveillance. Evaluated against European infectious disease case definitions, syndromic surveillance can contribute to identify cases that might fulfil the clinical case definition but the approach is too unspecific to comply to complete clinical definitions. Syndromic surveillance results still seem feasible for comparable cross-border surveillance as similarly defined syndromes are analysed. We suggest a new model of implementing syndromic surveillance at the subnational level. In this model, syndromic surveillance systems are fine-tuned to their local context and integrated into the existing subnational surveillance and reporting structure. By enhancing population coverage, events covering several jurisdictions can be identified at higher levels. However, the setup of decentralised and locally adjusted syndromic surveillance systems is more complex compared to the setup of one national or local system.

SUMMARY

We conclude that syndromic surveillance if implemented with large population coverage at the subnational level can help detect and assess the local and regional effect of different types of public health emergencies in a timely manner as required by the International Health Regulations (2005).

摘要

背景

修订后的世界卫生组织《国际卫生条例(2005)》要求对监测采取及时且涵盖所有危害的方法,尤其是在国家以下层面。我们讨论在欧洲背景下症状监测应用的三个问题,以评估国际关注的突发公共卫生事件:(i)症状监测能否支持各国,特别是国家以下层面,满足《国际卫生条例(2005)》的核心监测能力要求;(ii)欧洲的症状监测系统是否具有可比性以实现跨境监测;(iii)症状监测最适合在哪个行政层面应用?

讨论

尽管对症状监测的有用性一直存在批评,因其产出在临床上缺乏特异性,但我们证明它是及时评估影响欧洲的三种不同突发公共卫生事件影响的合适补充。在某些情况下,与国家层面分析相比,国家以下层面的症状监测分析在更早发现事件方面具有优势。然而,在许多情况下,症状监测未能检测到仅有少数病例的局部事件。欧盟委员会设想监测产出具有可比性以实现跨境监测。对照欧洲传染病病例定义进行评估,症状监测有助于识别可能符合临床病例定义的病例,但该方法过于缺乏特异性,无法完全符合临床定义。由于对类似定义的综合征进行了分析,症状监测结果对于可比的跨境监测似乎仍然可行。我们建议在国家以下层面实施症状监测的新模式。在该模式中,症状监测系统根据当地情况进行微调,并整合到现有的国家以下监测和报告结构中。通过扩大人群覆盖范围,可以在更高层面识别涉及多个辖区的事件。然而,与建立一个国家或地方系统相比,建立分散且针对当地调整的症状监测系统更为复杂。

总结

我们得出结论,若在国家以下层面以广泛的人群覆盖范围实施症状监测,可有助于及时检测和评估《国际卫生条例(2005)》要求的不同类型突发公共卫生事件的局部和区域影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b810/4324797/8efdd1ac1068/12889_2015_1421_Fig1_HTML.jpg

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