Escobedo de la Peña J, Escandón-Romero C, Escamilla-Cejudo J A, Franco-Marina F, Cervantes-Rangel J
Salud Publica Mex. 1989 Jul-Aug;31(4):473-80.
In spite of the widespread use of oral poliovirus vaccine, some countries have not achieved an optimal control of poliomyelitis. According to Sabin, this fact is due to a lack of immunization coverage of children under one year of age. In this study, the relationship between the general morbidity rate for polio and vaccination coverage of children under one year of age, in people protected by the Mexican Institute of Social Security, is analyzed. There is a negative correlation between these two variables: the lesser the coverage, the greater the rates. There is also a correlation between the rate of polio and the rate of polio for the year prior to each of the years of the study period. In a multiple regression model, both the coverage and the rate for the previous year were significantly correlated with the rate of polio. In order to get an optimum control of this disease, it is advantageous to consider that it is not enough to increase the coverage but that this coverage must be opportune, i.e., in the first year of life.
尽管口服脊髓灰质炎疫苗已广泛使用，但一些国家尚未实现对脊髓灰质炎的最佳控制。据萨宾称，这一事实是由于一岁以下儿童的免疫接种覆盖率不足。在本研究中，分析了墨西哥社会保障局所保护人群中脊髓灰质炎总体发病率与一岁以下儿童疫苗接种覆盖率之间的关系。这两个变量之间存在负相关：覆盖率越低，发病率越高。在研究期间的每一年中，脊髓灰质炎发病率与上一年的脊髓灰质炎发病率之间也存在相关性。在多元回归模型中，覆盖率和上一年的发病率均与脊髓灰质炎发病率显著相关。为了实现对这种疾病的最佳控制，有必要考虑到仅提高覆盖率是不够的，而且这种覆盖率必须及时，即在生命的第一年。
