Zhang Shao-Qun, Wang Yan-Jie, Zhang Ji-Ping, Chen Jun-Qi, Wu Chun-Xiao, Li Zhi-Peng, Chen Jia-Rong, Ouyang Huai-Liang, Huang Yong, Tang Chun-Zhi
School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province, China.
First Clinical School, Southern Medical University, Guangzhou, Guangdong Province, China.
Neural Regen Res. 2015 Feb;10(2):292-7. doi: 10.4103/1673-5374.152385.
Acupuncture can induce changes in the brain. However, the majority of studies to date have focused on a single acupoint at a time. In the present study, we observed activity changes in the brains of healthy volunteers before and after acupuncture at Taichong (LR3) and Taixi (KI3) using resting-state functional magnetic resonance imaging. Fifteen healthy volunteers underwent resting-state functional magnetic resonance imaging of the brain 15 minutes before acupuncture, then received acupuncture at Taichong and Taixi using the nail-pressing needle insertion method, after which the needle was retained in place for 30 minutes. Fifteen minutes after withdrawal of the needle, the volunteers underwent a further session of resting-state functional magnetic resonance imaging, which revealed that the amplitude of low-frequency fluctuation, a measure of spontaneous neuronal activity, increased mainly in the cerebral occipital lobe and middle occipital gyrus (Brodmann area 18/19), inferior occipital gyrus (Brodmann area 18) and cuneus (Brodmann area 18), but decreased mainly in the gyrus rectus of the frontal lobe (Brodmann area 11), inferior frontal gyrus (Brodmann area 44) and the center of the posterior lobe of the cerebellum. The present findings indicate that acupuncture at Taichong and Taixi specifically promote blood flow and activation in the brain areas related to vision, emotion and cognition, and inhibit brain areas related to emotion, attention, phonological and semantic processing, and memory.
针刺可引起大脑的变化。然而,迄今为止的大多数研究一次仅聚焦于单个穴位。在本研究中,我们使用静息态功能磁共振成像观察了健康志愿者在针刺太冲(LR3)和太溪(KI3)前后大脑的活动变化。15名健康志愿者在针刺前15分钟接受大脑静息态功能磁共振成像,然后采用指压进针法针刺太冲和太溪,之后留针30分钟。拔针15分钟后,志愿者再次接受静息态功能磁共振成像,结果显示,作为自发神经元活动指标的低频波动幅度主要在枕叶、枕中回(布罗德曼区18/19)、枕下回(布罗德曼区18)和楔叶(布罗德曼区18)增加,但主要在额叶直回(布罗德曼区11)、额下回(布罗德曼区44)和小脑后叶中部减少。本研究结果表明,针刺太冲和太溪可特异性促进与视觉、情感和认知相关脑区的血流和激活,并抑制与情感、注意力、语音和语义处理及记忆相关的脑区。