Croden Jennifer, Ross Sue, Yuksel Nese, Sydora Beate C
Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry, University of Alberta, 5S131 Lois Hole Hospital for Women, Robbins Pavilion, Royal Alexandra Hospital, 10240 Kingsway Avenue NW, Edmonton, AB, T5H 3 V9, Canada.
Faculty of Pharmacy and Pharmaceutical Sciences, 3-171 Edmonton Clinic Health Academy, 11405 - 87 Avenue NW, Edmonton, AB, T6G 1C9, Canada.
BMC Complement Altern Med. 2015 Mar 27;15:86. doi: 10.1186/s12906-015-0608-5.
Menopause is a natural phase in a woman's aging process, characterized by the cessation of menstruation. Women who are going through the menopause transition can experience physiological symptoms that significantly impact their quality of life. Concern about adverse effects of traditional hormone therapy often leads women to purchase over-the-counter (OTC) natural health products (NHPs). The goal of this study was toinvestigate the range of OTC NHPs for menopause available to Canadian women, and the packaging information they can access to make self-management decisions.
Edmonton stores belonging to each of nine Canadian pharmacy chains were visited to identify NHPs marketed for the relief of menopausal symptoms. Details were extracted from the packaging: a) product name and manufacturer, b) Health Canada license number, c) medically active ingredients, d) claims of efficacy, e) contra-indications and warnings, and f) daily cost. Data were entered and analyzed using Microsoft Excel.
We identified 20 OTC NHP menopausal products, 19 of which had Health Canada license numbers. Twenty-eight medically active ingredients were identified, with the most common being black cohosh (in 14 products) and soy isoflavones (n = 7), chaste tree (n = 5), and dong quai (n = 3). Most products claimed they would relieve vasomotor symptoms, including hot flashes (n = 14) and night sweats (n = 10). Each product had a labeled contraindication for at least one specific condition. Costs per recommended daily dose ranged from $0.07 to a maximum of $2.50 (CAD$).
Natural health products for menopausal symptoms are easily available to Canadian women. The lack of clear evidence of product efficacy makes the need for easily accessible, balanced information on this topic important for women to make well informed choices.
更年期是女性衰老过程中的一个自然阶段,其特征是月经停止。正在经历更年期过渡的女性可能会出现生理症状,这些症状会显著影响她们的生活质量。对传统激素疗法不良反应的担忧常常导致女性购买非处方(OTC)天然健康产品(NHPs)。本研究的目的是调查加拿大女性可获得的用于更年期的非处方天然健康产品范围,以及她们可获取的用于自我管理决策的包装信息。
走访了加拿大九家连锁药店在埃德蒙顿的门店,以确定用于缓解更年期症状的天然健康产品。从包装上提取详细信息:a)产品名称和制造商,b)加拿大卫生部许可证编号,c)医学活性成分,d)功效宣称,e)禁忌症和警告,以及f)每日费用。数据使用Microsoft Excel录入和分析。
我们识别出20种非处方天然健康更年期产品,其中19种有加拿大卫生部许可证编号。识别出28种医学活性成分,最常见的是黑升麻(14种产品含有)、大豆异黄酮(n = 7)、贞节树(n = 5)和当归(n = 3)。大多数产品宣称它们能缓解血管舒缩症状,包括潮热(n = 14)和盗汗(n = 10)。每种产品都有至少一种特定病症的标签禁忌症。每推荐每日剂量的费用从0.07加元到最高2.50加元不等。
加拿大女性很容易获得用于缓解更年期症状的天然健康产品。缺乏产品功效的确切证据使得提供易于获取的、关于该主题的平衡信息对于女性做出明智选择很重要。