Vlasov A V, Zurochka A V, Dolgushin I I
Zh Mikrobiol Epidemiol Immunobiol. 1989 Aug(8):73-6.
The influence of the products secreted by activated neutrophils (neutrophilokins) of mice, both intact and infected with staphylococci, on the activity of mouse spleen cells in the graft-versus-host reaction, immune response to sheep red blood cells and the antigen-presenting function of peritoneal macrophages was studied. Neutrophilokins of intact mice stimulated the activity of immunocompetent cells. Neutrophilokins obtained from infected mice on day 3 after infection produced an immunosuppressing effect. On day 7 after infection the immunostimulating activity of neutrophils was restored and showed practically no difference from the normal level.
研究了完整小鼠以及感染葡萄球菌的小鼠体内活化中性粒细胞分泌的产物（中性粒细胞素）对小鼠脾细胞在移植物抗宿主反应、对绵羊红细胞的免疫反应及腹腔巨噬细胞抗原呈递功能中的活性的影响。完整小鼠的中性粒细胞素刺激免疫活性细胞的活性。感染后第3天从感染小鼠获得的中性粒细胞素产生免疫抑制作用。感染后第7天，中性粒细胞的免疫刺激活性恢复，与正常水平几乎没有差异。
