Prat Jaime
Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain.
Best Pract Res Clin Obstet Gynaecol. 2015 Aug;29(6):858-69. doi: 10.1016/j.bpobgyn.2015.03.006. Epub 2015 Mar 31.
Ovarian, fallopian tube, and peritoneal cancers have a similar clinical presentation and are treated similarly, and current evidence supports staging all three cancers in a single system. The primary site (i.e., ovary, fallopian tube, or peritoneum) should be designated where possible. The histologic type should be recorded. Intraoperative rupture ("surgical spill") is IC1; capsule ruptured before surgery or tumor on ovarian or fallopian tube surface is IC2; and positive peritoneal cytology with or without rupture is IC3. The new staging includes a revision of stage III patients; assignment to stage IIIA1 is based on spread to the retroperitoneal lymph nodes without intraperitoneal dissemination. Extension of the tumor from the omentum to the spleen or liver (stage IIIC) should be differentiated from isolated parenchymal metastases (stage IVB).
卵巢癌、输卵管癌和腹膜癌具有相似的临床表现且治疗方式类似,目前的证据支持将这三种癌症纳入单一系统进行分期。应尽可能明确原发部位(即卵巢、输卵管或腹膜)。组织学类型也应记录。术中破裂(“手术播散”)为IC1;手术前包膜破裂或卵巢或输卵管表面有肿瘤为IC2;无论有无破裂,腹腔细胞学检查阳性为IC3。新的分期包括对III期患者的重新分类;III A1期是基于肿瘤扩散至腹膜后淋巴结而无腹腔内播散来判定。肿瘤从大网膜延伸至脾脏或肝脏(IIIC期)应与孤立的实质脏器转移(IVB期)相区分。