Prat Jaime
Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain.
Cancer. 2015 Oct 1;121(19):3452-4. doi: 10.1002/cncr.29524. Epub 2015 Jun 25.
Ovarian, fallopian tube, and peritoneal cancers have a similar clinical presentation and are treated similarly, and current evidence supports staging all 3 cancers in a single system. The primary site (i.e. ovary, fallopian tube, or peritoneum) should be designated where possible. The histologic type should be recorded. Intraoperative rupture ("surgical spill") is IC1; capsule ruptured before surgery or tumor on ovarian or fallopian tube surface is IC2; and positive peritoneal cytology with or without rupture is IC3. The new staging includes a revision of stage III patients; assignment to stage IIIA1 is based on spread to the retroperitoneal lymph nodes without intraperitoneal dissemination. Extension of tumor from omentum to spleen or liver (stage IIIC) should be differentiated from isolated parenchymal metastases (stage IVB).
卵巢癌、输卵管癌和腹膜癌具有相似的临床表现且治疗方式类似,目前的证据支持将这三种癌症纳入单一系统进行分期。应尽可能确定原发部位(即卵巢、输卵管或腹膜)。应记录组织学类型。术中破裂(“手术播散”)为IC1;术前包膜破裂或卵巢或输卵管表面有肿瘤为IC2;无论有无破裂,腹膜细胞学检查阳性为IC3。新分期包括对III期患者的修订;III A1期的判定依据是肿瘤扩散至腹膜后淋巴结但无腹腔内播散。肿瘤从大网膜延伸至脾脏或肝脏(IIIC期)应与孤立的实质转移(IVB期)相区分。