Makimoto Hisaki, Heeger Christian-H, Lin Tina, Rillig Andreas, Metzner Andreas, Wissner Erik, Mathew Shibu, Deiss Sebastian, Rausch Peter, Lemeš Christine, Kuck Karl-Heinz, Ouyang Feifan, Tilz Roland Richard
Department of Cardiology, Asklepios Klinik St Georg, Lohmuehlenstr 5, 20099, Hamburg, Germany.
Clin Res Cardiol. 2015 Oct;104(10):861-70. doi: 10.1007/s00392-015-0855-y. Epub 2015 Apr 18.
The aim of this study was to evaluate the impact of contact force (CF) visualization on the incidence of low and high CF during left atrial (LA) mapping and pulmonary vein isolation (PVI).
CF was assessed in 70 patients who underwent PVI. Three highly experienced operators performed all procedures. The operators were blinded to CF in group A (35 patients), and CF was displayed in group B (35 patients). In group B, optimal CF was defined as mean CF between 10 and 39g, and operators attempted to acquire points and ablate within this range.
A total of 8401 mapping points were analyzed during LA mapping (group A: 4104, group B: 4297). Low CF <10g and high CF ≥40g were noted in a significantly larger number of points in group A (37.7 vs. 12.0 %, P < 0.001; 11.5 vs. 1.5 %, P < 0.001). At the mitral isthmus and ridge areas, CF was significantly lower (7.7 vs. 12.2g, P < 0.001; 5.3 vs. 11.7g, P < 0.001) in group A than in group B. PVI was successfully achieved in all patients. There were significant site-dependent CF differences between the two groups. Optimal CF was achieved in significantly more applications in group B (P < 0.001). There was no significant difference in atrial fibrillation (AF) recurrence rates after a minimum follow-up of 1 year between the two groups in this cohort (P = 0.24). No significant peri-procedural complications occurred in either group.
CF visualization can assist in avoiding both low and high CF, which may have the potential to improve lesion formation and patient safety profile. In this study, CF-guided ablation did not affect AF recurrence.
本研究旨在评估接触力(CF)可视化对左心房(LA)标测及肺静脉隔离(PVI)过程中低接触力和高接触力发生率的影响。
对70例行PVI的患者进行接触力评估。由三名经验丰富的操作者完成所有手术。A组(35例患者)的操作者对接触力情况不知情,B组(35例患者)则显示接触力。在B组中,最佳接触力定义为平均接触力在10至39克之间,操作者试图在此范围内获取标测点并进行消融。
在LA标测期间共分析了8401个标测点(A组:4104个,B组:4297个)。A组中低接触力<10克和高接触力≥40克的标测点数量明显更多(37.7%对12.0%,P<0.001;11.5%对1.5%,P<0.001)。在二尖瓣峡部和嵴部区域,A组的接触力明显低于B组(7.7克对12.2克,P<0.001;5.3克对11.7克,P<0.001)。所有患者均成功完成PVI。两组之间存在明显的部位依赖性接触力差异。B组在更多的操作中实现了最佳接触力(P<0.001)。在该队列中,两组患者在至少随访1年后的房颤(AF)复发率无显著差异(P = 0.24)。两组均未发生明显的围手术期并发症。
接触力可视化有助于避免低接触力和高接触力,这可能有助于改善损伤形成和患者安全状况。在本研究中,接触力引导下的消融并未影响房颤复发。