Bohara Raghvendra A, Pawar Shivaji H
Center for Interdisciplinary Research, D.Y. Patil University, Kolhapur, 416006, M.S., India,
Appl Biochem Biotechnol. 2015 Jun;176(4):1044-58. doi: 10.1007/s12010-015-1628-9. Epub 2015 Apr 18.
It has been seen from the last decade that many bacterial strains are becoming insensitive to conventional detection techniques and it has its own limitations. Current developments in nanoscience and nanotechnology have expanded the ability to design and construct nanomaterials with targeting, therapeutic, and diagnostic functions. These multifunctional nanomaterials have attracted researchers, to be used as the promising tool for selective bacterial sensing applications. An important advantage of using magnetic nanoparticles to capture bacteria is the simple separation of bacteria from biological samples using magnets. This review includes significance of magnetic nanoparticles in bacterial detection. Relevant to topic, properties, designing strategies for magnetic nanoparticle, and innovative techniques used for detection are discussed. This review provides the readers how magnetic properties of nanoparticles can be utilized systematically for bacterial identification.
从过去十年可以看出，许多细菌菌株对传统检测技术变得不敏感，并且传统检测技术有其自身的局限性。纳米科学和纳米技术的当前发展扩展了设计和构建具有靶向、治疗和诊断功能的纳米材料的能力。这些多功能纳米材料吸引了研究人员，有望用作选择性细菌传感应用的工具。使用磁性纳米颗粒捕获细菌的一个重要优点是可以使用磁铁从生物样品中简单地分离细菌。本综述包括磁性纳米颗粒在细菌检测中的重要性。讨论了与主题相关的磁性纳米颗粒的性质、设计策略以及用于检测的创新技术。本综述向读者介绍了如何系统地利用纳米颗粒的磁性进行细菌鉴定。
