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伊朗亚苏季高危人群中基于人群的2型糖尿病筛查。

A population-based screening of type 2 diabetes in high-risk population of Yasuj, Iran.

作者信息

Safari Mitra, Yazdanpanah Behrouz, Yazdanpanah Behzad, Mobasheri Ali

出版信息

J Health Popul Nutr. 2014 Dec;32(4):677-86.

Abstract

Complications associated with diabetes can be prevented by early diagnostics. A high-risk population was screened for diabetes, and the prevalence of undiagnosed diabetes mellitus (DM) and impaired fasting glucose (IFG) were used for examining the impacts of lifestyle, social and anthropometric features, and other risk factors. The target population comprised 30-65 years old residents from the western suburbs of Yasuj. Homes were approached, and a standard questionnaire was used for collecting information on sex, blood pressure, weight, height, and BMI for each participant. The high-risk participants were recognized according to the National Diabetes Prevention and Control Committee criteria and were introduced to an assigned laboratory. Blood samples were collected after 12-hour fasting for the measurement of total cholesterol, triglycerides and fasting glucose levels. The statistical analysis was performed with the SPSS statistical package, using a logistic regression model. Out of 2,569 individuals, 1,336 (52%) were with high-risk diabetes, 71.5% were female, and 28.5% were male. Of 191 (7.4%) individuals with known diabetes, 5 (2.6%) had type 1 diabetes; 881 (66.9%) out of 1,336 high-risk individuals were referred to assigned laboratory. Of 881 high-risk individuals, 157 (17.8%) had fasting blood sugar (FBS) 126 mg/dL and 118 (13.4%) had FBS between110 and 125 mg/dL. Percentages of participants with triglyceride ?150 mg/dL and cholesterol ?200 mg/dL were 298 (33.8%) and 207 (23.5%) respectively. Diabetes was associated with ageing, dyslipidaemia, family history of diabetes, lower physical activity on occupation, intake of lower dietary fibre, and non-literacy in the sampled population. This study suggests that diabetes is a common health problem in this area. Furthermore, considerable rate of newly-diagnosed diabetes signifies the importance of the screening programme.

摘要

糖尿病相关并发症可通过早期诊断得以预防。对高危人群进行糖尿病筛查,并利用未诊断糖尿病(DM)和空腹血糖受损(IFG)的患病率来考察生活方式、社会和人体测量特征以及其他风险因素的影响。目标人群为亚苏杰西郊30至65岁的居民。研究人员走访各家各户,并使用标准问卷收集每位参与者的性别、血压、体重、身高和体重指数(BMI)信息。高危参与者根据国家糖尿病防控委员会的标准进行认定,并被送往指定实验室。在禁食12小时后采集血样,以测量总胆固醇、甘油三酯和空腹血糖水平。使用SPSS统计软件包并通过逻辑回归模型进行统计分析。在2569名个体中,1336名(52%)患有高危糖尿病,其中71.5%为女性,28.5%为男性。在191名(7.4%)已知患有糖尿病的个体中,5名(2.6%)患有1型糖尿病;1336名高危个体中有881名(66.9%)被送往指定实验室。在881名高危个体中,157名(17.8%)空腹血糖(FBS)≥126mg/dL,118名(13.4%)空腹血糖在110至125mg/dL之间。甘油三酯≥150mg/dL和胆固醇≥200mg/dL的参与者百分比分别为298名(33.8%)和207名(23.5%)。在抽样人群中,糖尿病与年龄增长、血脂异常、糖尿病家族史、职业体力活动较少、膳食纤维摄入量较低以及文盲有关。本研究表明,糖尿病在该地区是一个常见的健康问题。此外,新诊断糖尿病的相当比例表明了筛查计划的重要性。

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