Luciano Nicoletta, Valentini Valentina, Calabrò Andrea, Elefante Elena, Vitale Antonio, Baldini Chiara, Bartoloni Elena
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Department of Rheumatology, University of Perugia, Perugia, Italy.
Clin Exp Rheumatol. 2015 Mar-Apr;33(2):259-71. Epub 2015 Apr 10.
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease mainly characterised by the inflammation of exocrine glands; however, a broad spectrum of systemic manifestations may characterise the disease. Recently, pSS has been the object of considerable immunologic and clinical research which has led to significant advances in the diagnosis, prognostic assessment and management of the disease. Herewith, we provide a critical digest of the recent literature on this topic.
原发性干燥综合征（pSS）是一种慢性自身免疫性疾病，主要特征为外分泌腺炎症；然而，该疾病可能具有广泛的全身表现。最近，pSS成为了大量免疫学和临床研究的对象，这些研究在该疾病的诊断、预后评估和管理方面取得了显著进展。在此，我们提供关于这一主题的近期文献的关键摘要。
