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老年与放弃治疗:荷兰一项全国性死亡率随访研究

Old age and forgoing treatment: a nationwide mortality follow-back study in the Netherlands.

作者信息

Martins Pereira Sandra, Pasman H Roeline, van der Heide Agnes, van Delden Johannes J M, Onwuteaka-Philipsen Bregje D

机构信息

Department of Public and Occupational Health, EMGO Institute for Health and Care research, Expertise Center for Palliative Care, VU University Medical Center, The Netherlands.

Department of Public Health, ERASMUS MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

出版信息

J Med Ethics. 2015 Sep;41(9):766-70. doi: 10.1136/medethics-2014-102367. Epub 2015 Apr 20.

Abstract

BACKGROUND

The ageing of the population raises the need to study forgoing treatment decisions among older people.

AIM

To describe the incidence and decision-making of forgoing treatment and identify age-related differences.

METHODS

A nationwide study of a stratified sample from the Statistics Netherlands death registry to which all deaths were reported in 2010. All attending physicians of those deaths received a questionnaire about end-of-life decisions. 6600 cases were studied. We examined three age groups: 17-64, 65-79, and 80 and above. Logistic regression analyses were performed to identify age-related differences controlling for other patient characteristics.

RESULTS

Forgoing treatment occurred in 37% of the total population, with a significant increase in the incidence across age. The most common treatments withheld/withdrawn were artificial hydration/nutrition, medication and antibiotics. Age-related differences were found, especially for withholding artificial hydration/nutrition among patients aged 65-79 (OR 2.04), and for withdrawing medication (OR 2.51) and antibiotics (OR 2.10) among the oldest when compared to the youngest patients. The most common reason for making the decision was 'no chance of improvement'. The likelihood of forgoing treatment due to 'loss of dignity' was higher for the oldest (OR 2.32), as well as due to the request/wish of the patient (OR 1.97), when compared to the youngest patients.

CONCLUSIONS

Forgoing treatment occurred in a substantial proportion of older people, and more often than in younger age groups. The avoidance of burdensome treatment solely to prolong life suggests a better acceptance that these patients are nearing death.

摘要

背景

人口老龄化增加了研究老年人放弃治疗决策的必要性。

目的

描述放弃治疗的发生率和决策情况,并确定与年龄相关的差异。

方法

对荷兰统计局死亡登记处的分层样本进行全国性研究,2010年所有死亡病例均已上报。这些死亡病例的所有主治医生都收到了一份关于临终决策的问卷。共研究了6600例病例。我们考察了三个年龄组:17 - 64岁、65 - 79岁和80岁及以上。进行逻辑回归分析以确定在控制其他患者特征的情况下与年龄相关的差异。

结果

37%的总人口出现了放弃治疗的情况,且发生率随年龄显著增加。最常被停止/撤销的治疗是人工补液/营养、药物和抗生素。发现了与年龄相关的差异,特别是65 - 79岁患者中停止人工补液/营养的情况(比值比2.04),以及与最年轻患者相比,最年长患者中撤销药物(比值比2.51)和抗生素(比值比2.10)的情况。做出决策最常见的原因是“没有改善的机会”。与最年轻患者相比,最年长患者因“失去尊严”(比值比2.32)以及因患者的请求/愿望(比值比1.97)而放弃治疗的可能性更高。

结论

相当一部分老年人出现了放弃治疗的情况,且比年轻人群体更常见。仅为延长生命而避免繁重治疗表明这些患者更能接受自己已接近死亡。

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