乌干达东部糖尿病患者的抗糖尿病药物依从性；一项横断面研究。
Adherence to anti diabetic medication among patients with diabetes in eastern Uganda; a cross sectional study.
作者信息
Bagonza James, Rutebemberwa Elizeus, Bazeyo William
机构信息
Department of Health Policy, Planning and Management, School of Public Health, Makerere University College of Health Sciences, Kampala, Uganda.
Department of Disease Control and Environmental Health, School of Public Health, Makerere University College of Health Sciences, Kampala, Uganda.
出版信息
BMC Health Serv Res. 2015 Apr 19;15:168. doi: 10.1186/s12913-015-0820-5.
BACKGROUND
Lack of adherence to anti diabetic medication causes suboptimal blood sugar control among patients with diabetes and can lead to treatment failures, accelerated development of complications and increased mortality. This study assessed factors associated with adherence to anti diabetic medication in rural eastern Uganda.
METHODS
A cross sectional study was conducted among 521 patients with diabetes in Iganga and Bugiri hospitals between October 2012 and January 2013. Respondents were patients who were18 years and above and had been on diabetic treatment for not less than a month. Pretested questionnaires were used. Variables that were collected included socio-demographic characteristics, possible barriers to adherence, and self management efforts. Adherence was assessed using self reports. Descriptive and inferential statistics were done to determine adherence to anti diabetic medication and the associated factors.
RESULTS
The level of adherence to anti diabetic medication was 83.3% and factors that were independently associated with adherence were; having been on anti diabetic drugs for at least three years (OR = 1.89, 95% CI = 1.11 - 3.22), availability of diabetic drugs (OR = 2.59, 95% CI = 1.54 - 3.70), and having ever had diabetic health education (OR = 4.24, 95% CI =1.15 - 15.60).
CONCLUSION
About four in five patients adhere to anti-diabetic treatment. Strategies aimed at improving anti diabetic drug availability and providing health education could improve adherence.
背景
糖尿病患者不坚持服用抗糖尿病药物会导致血糖控制不理想，并可能导致治疗失败、并发症加速发展和死亡率增加。本研究评估了乌干达东部农村地区与抗糖尿病药物依从性相关的因素。
方法
2012年10月至2013年1月期间，在伊甘加和布吉里医院对521名糖尿病患者进行了一项横断面研究。受访者为18岁及以上且接受糖尿病治疗不少于一个月的患者。使用经过预测试的问卷。收集的变量包括社会人口学特征、依从性可能的障碍以及自我管理努力。通过自我报告评估依从性。进行描述性和推断性统计以确定抗糖尿病药物的依从性及其相关因素。
结果
抗糖尿病药物的依从性水平为83.3%，与依从性独立相关的因素有：服用抗糖尿病药物至少三年（OR = 1.89，95% CI = 1.11 - 3.22）、有糖尿病药物可用（OR = 2.59，95% CI = 1.54 - 3.70）以及曾接受糖尿病健康教育（OR = 4.24，95% CI = 1.15 - 15.60）。
结论
约五分之四的患者坚持抗糖尿病治疗。旨在提高抗糖尿病药物可及性并提供健康教育的策略可能会提高依从性。
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