Ali Muhammed, Alemu Tigestu, Sada Oumer
Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
BMC Res Notes. 2017 Dec 4;10(1):676. doi: 10.1186/s13104-017-3025-7.
Diabetes is a global problem with devastating human, social and economic impact. Anti-diabetic medications play a major role in the glycemic control of patients with diabetes. However, inadequate adherence compromises safety and treatment effectiveness, leading to increased mortality and morbidity. The aim of this study was to assess adherence to anti-diabetic medications and associated factors among patient with diabetes mellitus receiving care at Zewditu Memorial Hospital.
Among the total of 146 diabetic patients (mean age 46.5 ± 14.7), the level of adherence to anti diabetic medication was 54.8% (80) whilst 45.2% (66) of the participants were non adherent. Multiple logistic regression showed that knowledge of medication (AOR = 4.905, 95% CI 1.64-14.62, medication availability (AOR = 0.175, 95% CI 0.031-0.987) and education level (AOR = 13.65, 95% CI 1.45-128.456) were reasons for non-adherence.
糖尿病是一个全球性问题，对人类、社会和经济造成了毁灭性影响。抗糖尿病药物在糖尿病患者的血糖控制中起着重要作用。然而，依从性不足会影响安全性和治疗效果，导致死亡率和发病率上升。本研究的目的是评估在泽韦迪图纪念医院接受治疗的糖尿病患者对抗糖尿病药物的依从性及相关因素。
在总共146名糖尿病患者（平均年龄46.5±14.7岁）中，抗糖尿病药物的依从率为54.8%（80人），而45.2%（66人）的参与者不依从。多因素logistic回归显示，药物知识（比值比=4.905，95%置信区间1.64-14.62）、药物可及性（比值比=0.175，95%置信区间0.031-0.987）和教育水平（比值比=13.65，95%置信区间1.45-128.456）是不依从的原因。
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