干细胞研究

Stem Cell Research.

作者信息

Trounson Alan, Kolaja Kyle, Petersen Thomas, Weber Klaus, McVean Maralee, Funk Kathleen A

机构信息

Monash University, Hudson Institute for Medical Research, Clayton, Victoria, Australia.

Cellular Dynamics, Madison, WI, USA.

出版信息

Int J Toxicol. 2015 Jul-Aug;34(4):349-51. doi: 10.1177/1091581815581423. Epub 2015 Apr 20.

DOI:10.1177/1091581815581423

PMID:25899720

Abstract

Stem cells have great potential in basic research and are being slowly integrated into toxicological research. This symposium provided an overview of the state of the field, stem cell models, described allogenic stem cell treatments and issues of immunogenicity associated with protein therapeutics, and tehn concentrated on stem cell uses in regenerative medicine focusing on lung and testing strategies on engineered tissues from a pathologist's perspective.

摘要

干细胞在基础研究中具有巨大潜力，并且正逐渐融入毒理学研究。本次研讨会概述了该领域的现状、干细胞模型，介绍了同种异体干细胞治疗以及与蛋白质治疗相关的免疫原性问题，然后从病理学家的角度重点探讨了干细胞在再生医学中的应用，特别是肺部再生医学以及工程组织的测试策略。