Department of Operative/Restorative Dentistry, Periodontology and Pedodontics, Ludwig-Maximilians-University of Munich, Goethestr. 70, 80336 Munich, Germany; Walther-Straub-Institute of Pharmacology and Toxicology, Nussbaumstr. 26, 80336 Munich, Germany.
KU Leuven Biomat, Department of Oral Health Sciences KU Leuven, Kapucijnenvoer 7, 3000 Leuven, Belgium.
Dent Mater. 2015 Jun;31(6):745-57. doi: 10.1016/j.dental.2015.03.016. Epub 2015 Apr 18.
Bleaching treatments can affect on the polymer network of dental composites. This study was performed to evaluate the influence of different bleaching treatments on the elution of composite components.
The composites Tetric EvoCeram(®), CLEARFIL™ AP-X, Tetric EvoFlow(®), Filtek™ Supreme XT, Ceram X(®) mono+, Admira and Filtek™ Silorane were treated with the bleaching gels Opalescence PF 15% (PF 15%) for 5h and PF 35% (PF 35%) for 30 min and then stored in methanol and water for 24h and 7 d. The eluates were analyzed by gas chromatography/mass spectrometry (GC/MS). Unbleached specimens were used as control group.
A total of 16 different elutable substances have been identified from the investigated composites after bleaching-treatment. Six of them were methacrylates: 1,10-decandioldimethacrylate (DDDMA), 1,12-dodekandioldimethacrylate (DODDMA), ethylenglycoldimethacrylate (EGDMA), 2-hydroxyethylmethacrylate (HEMA), triethylenglycoldimethacrylate (TEGDMA) and urethandimethacrylate (UDMA). Compared with the unbleached controls the composites Tetric EvoCeram(®), CLEARFIL™ AP-X and Tetric EvoFlow(®) showed a reduced elution of UDMA, TEGDMA and HEMA after bleaching-treatment. Compared with the unbleached controls an increase elution of UDMA, DMABEE, BPA and TEGDMA for the composites Filtek™ Supreme XT, Ceram X(®) mono+, Admira and Filtek™ Silorane after bleaching-treatment has been detected. The highest concentration of UDMA was 0.01 mmol/l (Tetric EvoCeram(®), water, 24h, controls), the highest concentration of TEGDMA was 0.28 mmol/l (CLEARFIL™ AP-X, water, 7 d, controls), the highest concentration of HEMA was 0.74 mmol/l (Tetric EvoFlow(®), methanol, 7 d, PF 35%), the highest concentration of DMABEE was 0.10 mmol/l (Ceram X(®) mono+, water, 7 d, PF 35%) and the highest concentration of BPA was 0.01 mmol/l (Admira, methanol, 7 d, controls).
Bleaching treatments can lead to a reduced or an increased elution of substances from the dental composites.
漂白处理会影响牙科复合材料的聚合物网络。本研究旨在评估不同漂白处理对复合材料成分浸出的影响。
使用漂白凝胶 Opalescence PF 15%（PF 15%）处理 5 小时和 PF 35%（PF 35%）处理 30 分钟，对 Tetric EvoCeram（®）、CLEARFIL™ AP-X、Tetric EvoFlow（®）、Filtek™ Supreme XT、 Ceram X（®）mono+、Admira 和 Filtek™ Silorane 等七种复合材料进行处理，然后将其储存在甲醇和水中 24 小时和 7 天。使用气相色谱/质谱法（GC/MS）分析浸出物。未经过漂白处理的样本作为对照组。
经过漂白处理后，从研究的复合材料中鉴定出 16 种不同的可浸出物质。其中 6 种为甲基丙烯酸酯：1,10-癸二醇二甲基丙烯酸酯（DDDMA）、1,12-十二烷二醇二甲基丙烯酸酯（DODDMA）、乙二醇二甲基丙烯酸酯（EGDMA）、2-羟乙基甲基丙烯酸酯（HEMA）、三乙二醇二甲基丙烯酸酯（TEGDMA）和异氰脲酸三甲基丙烯酸酯（UDMA）。与未经过漂白处理的对照组相比，Tetric EvoCeram（®）、CLEARFIL™ AP-X 和 Tetric EvoFlow（®）在经过漂白处理后，UDMA、TEGDMA 和 HEMA 的浸出量减少。与未经过漂白处理的对照组相比，Filtek™ Supreme XT、 Ceram X（®）mono+、Admira 和 Filtek™ Silorane 等复合材料在经过漂白处理后，UDMA、DMABEE、BPA 和 TEGDMA 的浸出量增加。UDMA 的最高浓度为 0.01mmol/L（Tetric EvoCeram（®），水，24h，对照组），TEGDMA 的最高浓度为 0.28mmol/L（CLEARFIL™ AP-X，水，7d，对照组），HEMA 的最高浓度为 0.74mmol/L（Tetric EvoFlow（®），甲醇，7d，PF 35%），DMABEE 的最高浓度为 0.10mmol/L（ Ceram X（®）mono+，水，7d，PF 35%），BPA 的最高浓度为 0.01mmol/L（Admira，甲醇，7d，对照组）。
漂白处理可导致牙科复合材料中物质的浸出量减少或增加。
