de Carvalho Maira Peres, Türck Patrick, Abraham Wolf-Rainer
Helmholtz Centre for Infection Research, Chemical Microbiology.
Microbes Environ. 2015;30(2):196-8. doi: 10.1264/jsme2.ME14139. Epub 2015 Apr 23.
Fungi grow under humid conditions and are, therefore, prone to biofilm infections. A 16S rRNA fingerprint analysis was performed on 49 sporocarps of Basidiomycotina in order to determine whether they are able to control these biofilms. Ninety-five bacterial phylotypes, comprising 4 phyla and 10 families, were identified. While ectomycorrhizal fungi harbored the highest bacterial diversity, saprophytic fungi showed little or no association with bacteria. Seven fungal species were screened for antimicrobial and antibiofilm activities. Biofilm formation and bacterial growth was inhibited by extracts obtained from saprophytic fungi, which confirmed the hypothesis that many fungi modulate biofilm colonization on their sporocarps.
真菌在潮湿条件下生长，因此容易引发生物膜感染。为了确定担子菌亚门的49个子实体是否能够控制这些生物膜，对其进行了16S rRNA指纹分析。共鉴定出95种细菌系统型，分属4个门和10个科。虽然外生菌根真菌具有最高的细菌多样性，但腐生真菌与细菌的关联很少或没有关联。对7种真菌进行了抗菌和抗生物膜活性筛选。腐生真菌提取物可抑制生物膜形成和细菌生长，这证实了许多真菌可调节其子实体上生物膜定殖的假说。
