Physiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
Research Center for Modeling in Health, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Int J Health Policy Manag. 2014 Dec 23;4(5):271-7. doi: 10.15171/ijhpm.2015.06.
The goal of diabetes control should be feasible in order to minimize the risk of its adverse events and to reduce its burden and cost on patients. The current study aimed to assess the status of glycemic control in male and female patients with Type 2 Diabetes Mellitus (T2DM) in Kerman, Iran.
In the present study, 500 T2DM (300 women and 200 men) from the Kerman Coronary Artery Disease Risk Study (KERCADRS), a population-based study from 2009 to 2011, were selected. Patients were >18 years old, had Fasting Blood Sugar (FBS) higher than 126 mg/dl, and had been through treatment for their diagnosed disease. All participants underwent Glycosylated Hemoglobin (HbA1c) analysis. HbA1c less than 7% was considered as good glucose control. Other metabolic indices based on American Diabetes Association (ADA) target recommendations were considered.
The mean level of HbA1c in total subjects was 8.56 ± 4.72% that only 31.66% of men and 26.00% of women had controlled level of HbA1c. Total cholesterol less than 200 mg/dl was reported in 64.50% of men and 44.00% of women, High Density Lipoprotein (HDL) more than 40 mg/dl was revealed in 20.50% of men and 34.67% of women, and Low Density Lipoprotein (LDL) less than 100 mg/dl was reported in 41.50% of men and 25.33% of women. In multivariate logistic regression model, longer duration of disease and higher Waist Circumference (WC) were positively associated with uncontrolled diabetes status.
The findings of the present study revealed that diabetes control in T2DM was inadequate. Changing the policy of treatment in individual patient and establishing better diabetes clinic to decrease the frequency of uncontrolled T2DM are crucial. Paying attention to other affecting metabolic components such as WC in the process of T2DM management is important.
糖尿病控制的目标应该是可行的，以最大限度地降低其不良事件的风险，并降低其对患者的负担和成本。本研究旨在评估伊朗克尔曼 2 型糖尿病（T2DM）男性和女性患者的血糖控制状况。
本研究中，从 2009 年至 2011 年进行的基于人群的克尔曼冠状动脉疾病风险研究（KERCADRS）中选择了 500 名 T2DM 患者（300 名女性和 200 名男性）。患者年龄大于 18 岁，空腹血糖（FBS）高于 126mg/dl，并接受过诊断性疾病的治疗。所有参与者均进行了糖化血红蛋白（HbA1c）分析。HbA1c<7%被认为是良好的血糖控制。还考虑了基于美国糖尿病协会（ADA）目标建议的其他代谢指标。
总人群的平均 HbA1c 水平为 8.56±4.72%，仅有 31.66%的男性和 26.00%的女性达到了 HbA1c 的控制水平。总胆固醇<200mg/dl 报告在 64.50%的男性和 44.00%的女性中，高密度脂蛋白（HDL）>40mg/dl 在 20.50%的男性和 34.67%的女性中被揭示，低密度脂蛋白（LDL）<100mg/dl 在 41.50%的男性和 25.33%的女性中报告。在多变量逻辑回归模型中，疾病持续时间较长和腰围（WC）较高与糖尿病控制不佳呈正相关。
本研究的结果表明，T2DM 的糖尿病控制不足。改变个体患者的治疗策略并建立更好的糖尿病诊所以降低 T2DM 失控的频率至关重要。在 T2DM 管理过程中，注意 WC 等其他影响代谢的因素也很重要。
