Kenemans J L, Verbaten M N, Roelofs J W, Slangen J L
NIDDR, Department of Pharmacy, University of Utrecht, The Netherlands.
Biol Psychol. 1989 Jun;28(3):199-226. doi: 10.1016/0301-0511(89)90001-x.
The present study was concerned with brain potentials elicited by, respectively, the first of a series of stimuli ("initial-orienting reaction", I-OR), and infrequent deviants ("change-orienting reaction", C-OR). Single-trial event-related potentials (ERPs) to visual stimuli were estimated from recordings at Oz, Pz, Cz and Fz. The design included both a habituation series as well as a series of occasional deviant trials against a background of standards. This was done with both task-relevant and neutral stimuli, and in two interstimulus interval (ISI) conditions: 2.45 s and 8.45 s. In the latter ISI condition, skin conductance responses (SCRs) were recorded as well. Decrease (Habituation) in the habituation series was found for a non-specific N1, a posteriorly distributed P3, and the SCR, but not for P2-N2. Deviant stimuli produced an enhancement of the central P2-N2, the P3, the N1 (on the first few deviant trials only, in both ISI conditions), and the SCR (with task-relevant stimuli only). Elongation of ISI delayed both short-term and long-term decrease of P3, but had no effect on enhancement of P2-N2 due to stimulus deviance. It was concluded that, with respect to ERP parameters, the I-OR is marked by the N1, whereas the C-OR coincides with the P2-N2.
本研究关注的是分别由一系列刺激中的第一个（“初始定向反应”，I-OR）和罕见偏差刺激（“变化定向反应”，C-OR）引发的脑电位。通过在Oz、Pz、Cz和Fz处的记录来估计对视觉刺激的单次试验事件相关电位（ERP）。该设计包括一个习惯化系列以及在标准刺激背景下的一系列偶尔出现的偏差试验。这在与任务相关和中性刺激的情况下均进行，并且在两种刺激间隔（ISI）条件下：2.45秒和8.45秒。在后一种ISI条件下，还记录了皮肤电反应（SCR）。在习惯化系列中发现非特异性N1、后部分布的P3和SCR出现下降（习惯化），但P2-N2没有。偏差刺激导致中央P2-N2、P3、N1（仅在两种ISI条件下的前几次偏差试验中）和SCR（仅与任务相关刺激时）增强。ISI延长延迟了P3的短期和长期下降，但对由于刺激偏差导致的P2-N2增强没有影响。得出的结论是，就ERP参数而言，I-OR以N1为特征，而C-OR与P2-N2一致。
