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动态可调反射细胞中反射蛋白的结构、组织与功能

Structures, Organization, and Function of Reflectin Proteins in Dynamically Tunable Reflective Cells.

作者信息

DeMartini Daniel G, Izumi Michi, Weaver Aaron T, Pandolfi Erica, Morse Daniel E

机构信息

From the Biomolecular Science and Engineering Program, University of California, Santa Barbara, California 93106-9611, the Institute for Collaborative Biotechnologies, University of California, Santa Barbara, California 93106-5100, and.

the Institute for Collaborative Biotechnologies, University of California, Santa Barbara, California 93106-5100, and.

出版信息

J Biol Chem. 2015 Jun 12;290(24):15238-49. doi: 10.1074/jbc.M115.638254. Epub 2015 Apr 26.

Abstract

The reversible assembly of reflectin proteins drives dynamic iridescence in cephalopods. Squid dynamically tune the intensity and colors of iridescence generated by constructive interference from intracellular Bragg reflectors in specialized skin cells called iridocytes. Analysis of the tissue specificity of reflectin subtypes reveals that tunability is correlated with the presence of one specific reflectin sequence. Differential phosphorylation and dephosphorylation of the reflectins in response to activation by acetylcholine, as well as differences in their tissue-specific and subcellular spatial distributions, further support the suggestion of different roles for the different reflectin subtypes.

摘要

反射蛋白的可逆组装驱动头足类动物产生动态虹彩。鱿鱼通过位于称为虹彩细胞的特殊皮肤细胞内的细胞内布拉格反射器,利用相长干涉动态调节虹彩的强度和颜色。对反射蛋白亚型的组织特异性分析表明,可调节性与一种特定反射蛋白序列的存在相关。反射蛋白响应乙酰胆碱激活而发生的差异磷酸化和去磷酸化,以及它们在组织特异性和亚细胞空间分布上的差异,进一步支持了不同反射蛋白亚型具有不同作用的观点。

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