Turner D, Gray B J, Luzio S, Dunseath G, Bain S C, Hanley S, Richards A, Rhydderch D C, Ayles M, Kilduff L P, Campbell M D, West D J, Bracken R M
Applied Sports, Technology, Exercise and Medicine Research Centre, College of Engineering, Swansea University, Swansea, UK.
Diabetes Research Group, College of Medicine, Swansea University, Swansea, UK.
Scand J Med Sci Sports. 2016 Apr;26(4):404-12. doi: 10.1111/sms.12472. Epub 2015 Apr 28.
The aim of this study was to compare the glycemic and glucoregulatory hormone responses to low- and moderate-intensity morning resistance exercise (RE) sessions in type 1 diabetes (T1DM). Following maximal strength assessments (1RM), eight T1DM (HbA1C :72 ± 12 mmol/mol, age:34 ± 7 years, body mass index:25.7 ± 1.6 kg/m(2) ) participants attended the research facility on two separate occasions, having fasted and taken their usual basal insulin but omitting rapid-acting insulin. Participants performed six exercises for two sets of 20 repetitions at 30%1RM during one session [low-intensity RE session (LOW)] and two sets of 10 repetitions at 60%1RM during another session [moderate-intensity RE session (MOD)], followed by 65-min recovery. Sessions were matched for total mass lifted (kg). Venous blood samples were taken before and after exercise. Data (mean ± SEM) were analyzed using analysis of variance (P ≤ 0.05). There were no hypoglycemic occurrences throughout the study. Blood glucose rose similarly between sessions during exercise (P = 0.382), remaining comparable between sessions throughout recovery (P > 0.05). There was no effect of RE intensity on metabolic acidosis (P > 0.05) or peak growth hormone responses (P = 0.644), but a tendency for greater catecholamine responses under LOW (individualized peak concentrations: adrenaline MOD 0.55 ± 0.13 vs LOW 1.04 ± 0.37 nmol/L, P = 0.155; noradrenaline MOD 4.59 ± 0.86 vs LOW 7.11 ± 1.82 nmol/L, P = 0.082). The magnitude of post-exercise hyperglycemia does not differ between equal volume low and moderate intensity RE sessions performed in the morning.
本研究的目的是比较1型糖尿病（T1DM）患者对低强度和中等强度早晨抗阻运动（RE）的血糖和糖调节激素反应。在进行最大力量评估（1RM）后，8名T1DM患者（糖化血红蛋白：72±12 mmol/mol，年龄：34±7岁，体重指数：25.7±1.6 kg/m²）在两个不同的时间点前往研究机构，他们禁食并注射了常规基础胰岛素，但未注射速效胰岛素。参与者在一次训练中以30%1RM的强度进行6项运动，每组20次重复 [低强度抗阻运动训练（LOW）]，在另一次训练中以60%1RM的强度进行两组10次重复 [中等强度抗阻运动训练（MOD）]，随后进行65分钟的恢复。两次训练的总举重量（kg）相匹配。在运动前后采集静脉血样。数据（均值±标准误）采用方差分析进行分析（P≤0.05）。在整个研究过程中未发生低血糖事件。运动期间两组训练的血糖升高情况相似（P = 0.382），在整个恢复过程中两组之间仍具有可比性（P>0.05）。抗阻运动强度对代谢性酸中毒（P>0.05）或生长激素峰值反应（P = 0.644）没有影响，但在低强度训练下儿茶酚胺反应有增加的趋势（个体化峰值浓度：肾上腺素MOD为0.55±0.13 vs LOW为1.04±0.37 nmol/L，P = 0.155；去甲肾上腺素MOD为4.59±0.86 vs LOW为7.11±1.82 nmol/L，P = 0.082）。在早晨进行的等容量低强度和中等强度抗阻运动训练后，运动后高血糖的程度没有差异。
