人类第20号染色体标记的遗传连锁图谱。
A genetic linkage map of markers for human chromosome 20.
作者信息
Nakamura Y, Leppert M, O'Connell P, Lathrop M, Lalouel J M, White R
机构信息
Howard Hughes Medical Institute, University of Utah Medical School, Salt Lake City 84132.
出版信息
Genomics. 1989 Nov;5(4):945-7. doi: 10.1016/0888-7543(89)90139-0.
A continuous genetic linkage map with five polymorphic DNA markers, including one that defines a locus containing a variable number of tandem repeats (VNTR), has been constructed from genotypic analysis of 59 large reference families. The map spans a genetic distance of 105 cM in males and 115 cM in females and provides initial anchor points for a high-resolution map of human chromosome 20.
通过对59个大型参考家系的基因型分析，构建了一个包含五个多态性DNA标记的连续遗传连锁图谱，其中一个标记定义了一个含有可变数目串联重复序列（VNTR）的基因座。该图谱在男性中的遗传距离为105厘摩，在女性中的遗传距离为115厘摩，为人类20号染色体的高分辨率图谱提供了初始锚定点。
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