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等待时间与乳腺钼靶检查假阳性结果的心理社会后果:队列研究

Waiting time and the psychosocial consequences of false-positive mammography: cohort study.

作者信息

Heleno Bruno, Siersma Volkert, Brodersen John

机构信息

Department of Public Health, The Research Unit for General Practice and Section of General Practice, University of Copenhagen, Øster Farimagsgade 5, post-box 2099, 1014, Copenhagen K, Denmark.

出版信息

J Negat Results Biomed. 2015 Apr 30;14:8. doi: 10.1186/s12952-015-0028-6.

Abstract

BACKGROUND

There is wide variation in the psychosocial response to false-positive mammography. We aimed to assess whether women having to wait longer to exclude cancer had increased psychosocial consequences that persisted after cancer was ruled out.

FINDINGS

We selected women with false-positive mammography (n = 272), screened for breast cancer in Copenhagen and Funen (Denmark) over a 1-year period. We measured psychosocial consequences immediately before women attended their recall visit and 1, 6, 18 and 36 months after women received their final diagnosis. After women were told that cancer had been ruled out, adverse psychosocial consequences decreased with time. We found no statistically significant differences between women who had cancer ruled out immediately at the recall visit (waiting time of 0) and women who had to wait longer before cancer was ruled out (waiting times 1-30, 30-120 and > 120 days), when psychosocial consequences were measured via a condition-specific questionnaire (Consequences of Screening in Breast Cancer) at 5 time points (0, 1, 6, 18 and 36 months after cancer exclusion).

CONCLUSION

We did not confirm that waiting time was associated with worse long-term psychosocial consequences but type II error (failure to detect a true difference) might be a plausible explanation for our results.

摘要

背景

对乳腺钼靶检查假阳性的心理社会反应存在很大差异。我们旨在评估等待更长时间以排除癌症的女性是否会产生更多心理社会后果,且这些后果在癌症被排除后仍会持续。

研究结果

我们选择了在哥本哈根和菲英岛(丹麦)进行为期1年乳腺癌筛查的乳腺钼靶检查假阳性女性(n = 272)。我们在女性参加召回就诊前以及女性获得最终诊断后的1、6、18和36个月测量心理社会后果。在女性被告知癌症已被排除后,不良心理社会后果随时间减少。当通过特定疾病问卷(乳腺癌筛查的后果)在5个时间点(癌症排除后的0、1、6、18和36个月)测量心理社会后果时,我们发现召回就诊时立即排除癌症的女性(等待时间为0)与必须等待更长时间才能排除癌症的女性(等待时间为1 - 30天、30 - 120天和> 120天)之间没有统计学上的显著差异。

结论

我们没有证实等待时间与更差的长期心理社会后果相关,但II类错误(未能检测到真正差异)可能是我们结果的一个合理的解释。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db6f/4423128/45b8997b5285/12952_2015_28_Fig1_HTML.jpg

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