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使用认知测量方法解决精神分裂症患者及其亲属异质性的策略。

Strategies for resolving the heterogeneity of schizophrenics and their relatives using cognitive measures.

作者信息

Chapman L J, Chapman J P

出版信息

J Abnorm Psychol. 1989 Nov;98(4):357-66. doi: 10.1037//0021-843x.98.4.357.

DOI:10.1037//0021-843x.98.4.357
PMID:2592671
Abstract

The resolution of the heterogeneity of schizophrenics and their relatives using cognitive tasks requires measures of individual differences--usually of differential ability, which is inferred from differential performance. Tasks that are suited for establishing a group's differential ability are often unsuited for measuring individual differences. The problem is that for any group for which Tasks A and B have different mean accuracy, the (A - B) difference scores of individual subjects have an artifactual curvilinear relation to (A + B) overall accuracy, with the largest (A - B) scores occurring at about 50% (A + B) overall accuracy for a dichotomously scored free-response task. Two possible solutions are (a) to convert Task B scores to residualized scores, using the regression of Task B scores on Task A scores as determined for normal subjects; or (b) to titrate overall (A + B) accuracy of each subject to a constant level by manipulating a variable.

摘要

使用认知任务来解决精神分裂症患者及其亲属的异质性问题,需要测量个体差异——通常是差异能力,这是从不同表现中推断出来的。适合确定一组人差异能力的任务往往不适合测量个体差异。问题在于,对于任务A和任务B平均准确率不同的任何一组人来说,个体受试者的(A - B)差异分数与(A + B)总体准确率存在人为的曲线关系,对于二分计分的自由反应任务,最大的(A - B)分数出现在总体准确率约为50%(A + B)时。两种可能的解决方案是:(a)使用正常受试者确定的任务B分数对任务A分数的回归,将任务B分数转换为残差分数;或者(b)通过操纵一个变量,将每个受试者的总体(A + B)准确率调整到一个恒定水平。

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