Wang Qi, Larese-Casanova Philip, Webster Thomas J
Department of Bioengineering, College of Engineering, Northeastern University, Boston, MA, USA.
Department of Civil and Environmental Engineering, College of Engineering, Northeastern University, Boston, MA, USA.
Int J Nanomedicine. 2015 Apr 13;10:2885-94. doi: 10.2147/IJN.S78466. eCollection 2015.
There are wide spread bacterial contamination issues on various paper products, such as paper towels hanging in sink splash zones or those used to clean surfaces, filter papers used in water and air purifying systems, and wrappings used in the food industry; such contamination may lead to the potential spread of bacteria and consequent severe health concerns. In this study, selenium nanoparticles were coated on normal paper towel surfaces through a quick precipitation method, introducing antibacterial properties to the paper towels in a healthy way. Their effectiveness at preventing biofilm formation was tested in bacterial assays involving Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus epidermidis. The results showed significant and continuous bacteria inhibition with about a 90% reduction from 24 to 72 hours for gram-positive bacteria including S. aureus and S. epidermidis. The selenium coated paper towels also showed significant inhibition of gram-negative bacteria like P. aeruginosa and E. coli growth at about 57% and 84%, respectively, after 72 hours of treatment. Therefore, this study established a promising selenium-based antibacterial strategy to prevent bacterial growth on paper products, which may lead to the avoidance of bacteria spreading and consequent severe health concerns.
各种纸制品存在广泛的细菌污染问题，比如挂在水槽溅水区的纸巾或用于清洁表面的纸巾、水和空气净化系统中使用的滤纸以及食品工业中使用的包装纸；这种污染可能导致细菌的潜在传播以及随之而来的严重健康问题。在本研究中，通过快速沉淀法将硒纳米颗粒包覆在普通纸巾表面，以一种健康的方式赋予纸巾抗菌性能。在涉及金黄色葡萄球菌、铜绿假单胞菌、大肠杆菌和表皮葡萄球菌的细菌试验中测试了它们防止生物膜形成的有效性。结果显示，对于包括金黄色葡萄球菌和表皮葡萄球菌在内的革兰氏阳性菌，在24至72小时内有显著且持续的细菌抑制作用，抑制率约为90%。经过72小时处理后，包覆硒的纸巾对铜绿假单胞菌和大肠杆菌等革兰氏阴性菌的生长也分别有约57%和84%的显著抑制作用。因此，本研究建立了一种有前景的基于硒的抗菌策略，以防止纸制品上的细菌生长，这可能有助于避免细菌传播以及随之而来的严重健康问题。
