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在埃塞俄比亚西北部接受抗逆转录病毒治疗的艾滋病毒/艾滋病患者中持续使用避孕套:对减少传播和多重感染的意义

Consistent condom use in HIV/AIDS patients receiving antiretroviral therapy in northwestern Ethiopia: implication to reduce transmission and multiple infections.

作者信息

Shewamene Zewdneh, Legesse Befikadu, Tsega Bayew, Bhagavathula Akshaya Srikanth, Endale Abyot

机构信息

Department of Pharmacology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Department of Pharmacy, College of Medicine and Health Sciences, Mekelle University, Mekelle, Ethiopia.

出版信息

HIV AIDS (Auckl). 2015 Apr 13;7:119-24. doi: 10.2147/HIV.S79122. eCollection 2015.

Abstract

BACKGROUND

Human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) is one of the greatest public health problems of sub-Saharan African countries. Consistent condom use, among others, remains the most effective barrier method against HIV transmission. However, existing reports on frequency of consistent condom use have targeted the general public, rather than HIV/AIDS patients due, to the assumption that condom use is not important in HIV-infected persons. Since consistent condom use among HIV/AIDS patients is vital, to prevent the virus transmission from the infected to noninfected as well as to prevent multiple infections among already infected persons, its frequency and determining factors need to be investigated.

METHODS

A cross-sectional study was conducted from April 2013 to May 2013 among 317 randomly selected patients who were currently taking antiretroviral therapy (ART). Logistic regressions were performed to examine predictors of consistent condom use.

RESULTS

A total of 317 HIV/AIDS patients who were currently receiving ART participated in the study, and the mean age of the study population was 31.4 (standard deviation [SD] 10.5) years. Overall, 250 (78.9%) participants reported consistent condom use in the past 6 months. Of these, 140 (88.6%) were males and 110 (69.1%) females. Multivariate analysis indicated that respondents with an advanced level of education were more likely to report regular use of condoms (odds ratio [OR] 8.98; 95% confidence interval [CI] 5.06-14.45) compared with illiterate participants. Being male (OR 6.87; 95% CI 3.84-11.22), living in or around a town (OR 4.65; 95% CI 3.09-9.11), and taking ART for longer time (OR 3.91; 95% CI 2.07-6.25) were also positively associated with consistent condom use.

CONCLUSION

Females, patients living in rural areas, uneducated groups, and new ART users were less likely to use condoms consistently. The importance of consistent condom use should be well-addressed in HIV/AIDS patients, to prevent transmission and multiple infections of HIV.

摘要

背景

人类免疫缺陷病毒(HIV)/获得性免疫缺陷综合征(AIDS)是撒哈拉以南非洲国家最严重的公共卫生问题之一。坚持使用避孕套等措施仍然是预防HIV传播最有效的屏障方法。然而,现有的关于坚持使用避孕套频率的报告针对的是普通公众,而非HIV/AIDS患者,原因是假定在HIV感染者中使用避孕套并不重要。由于HIV/AIDS患者坚持使用避孕套对于防止病毒从感染者传播给未感染者以及预防已感染者发生多重感染至关重要,因此需要对其频率及决定因素进行调查。

方法

2013年4月至2013年5月,对317名随机选取的正在接受抗逆转录病毒治疗(ART)的患者进行了一项横断面研究。采用逻辑回归分析来检验坚持使用避孕套的预测因素。

结果

共有317名正在接受ART的HIV/AIDS患者参与了该研究,研究人群的平均年龄为31.4岁(标准差[SD]10.5)。总体而言,250名(78.9%)参与者报告在过去6个月中坚持使用避孕套。其中,140名(88.6%)为男性,110名(69.1%)为女性。多变量分析表明,与文盲参与者相比,受教育程度较高的受访者更有可能报告经常使用避孕套(比值比[OR]8.98;95%置信区间[CI]5.06 - 14.45)。男性(OR 6.87;95%CI 3.84 - 11.22)、居住在城镇或城镇周边地区(OR 4.65;95%CI 3.09 - 9.11)以及接受ART时间较长(OR 3.91;95%CI 2.07 - 6.25)也与坚持使用避孕套呈正相关。

结论

女性、居住在农村地区的患者、未受过教育的群体以及新接受ART治疗的患者坚持使用避孕套的可能性较小。应向HIV/AIDS患者充分强调坚持使用避孕套对于预防HIV传播和多重感染的重要性。

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