Luo S F, Huang C C, Wang J W
Taiwan Yi Xue Hui Za Zhi. 1989 Aug;88(8):832-5.
We present the first report of neonatal lupus erythematosus from Taiwan. A female baby, born to a mother with documented systemic lupus erythematosus (SLE), developed cutaneous lupus lesions after phototherapy for hyperbilirubinemia. She had additional clinical features of hemolytic anemia and thrombocytopenia. Detailed serological and immunogenetic studies were performed. Transplacental passage of both anti-SSA/Ro and anti-SSB/La antibodies were demonstrated and their disappearance at the age of 6 months correlated with regression of clinical symptoms. This patient inherited human leukocyte antigen (HLA) A11, Bw60 Cw3, DR2 and Aw33, Bw57, Cw7, DRw6 from her father and mother, respectively. A long-term follow-up is required for observing whether she will develop SLE in the future.
我们报告首例来自台湾的新生儿红斑狼疮病例。一名女婴，其母亲患有确诊的系统性红斑狼疮（SLE），在因高胆红素血症接受光疗后出现皮肤狼疮病变。她还具有溶血性贫血和血小板减少的其他临床特征。进行了详细的血清学和免疫遗传学研究。证实了抗SSA/Ro和抗SSB/La抗体均经胎盘传递，且它们在6个月龄时消失与临床症状消退相关。该患者分别从父亲和母亲那里遗传了人类白细胞抗原（HLA）A11、Bw60、Cw3、DR2以及Aw33、Bw57、Cw7、DRw6。需要进行长期随访以观察她未来是否会发展为SLE。
