Shanaube Kwame, Bock Peter
Zambart, Box 50697, Ridgeway Campus, Ridgeway, Lusaka, Zambia,
Curr HIV/AIDS Rep. 2015 Jun;12(2):231-7. doi: 10.1007/s11904-015-0262-z.
For the last three decades, sub-Saharan Africa has been the epicentre of the HIV epidemic. Some key drivers of the epidemic are specific to this region and there is an urgent need to develop context-specific strategies to reduce HIV-related burden. Implementation frameworks should endeavour to combine structural, behavioural and biomedical interventions and the future of the HIV response involves embracing different approaches for different populations; it is not 'one-size fits all approach'. Expanded use of community-based interventions will be key in expanding the role of antiretroviral treatment as prevention (TasP) in the region. For TasP to be effective, high antiretroviral therapy (ART) coverage rates need to be attained. Data from programmatic trials currently underway will provide crucial data to guide the future implementation of TasP.
在过去三十年里，撒哈拉以南非洲地区一直是艾滋病毒疫情的中心。该疫情的一些关键驱动因素是该地区所特有的，因此迫切需要制定因地制宜的战略，以减轻与艾滋病毒相关的负担。实施框架应努力将结构性、行为性和生物医学干预措施结合起来，应对艾滋病毒的未来发展需要针对不同人群采用不同方法；不存在“一刀切”的办法。扩大基于社区的干预措施的使用，将是扩大抗逆转录病毒治疗作为预防手段（治疗即预防）在该地区作用的关键。为使治疗即预防有效，需要实现较高的抗逆转录病毒疗法（ART）覆盖率。目前正在进行的项目试验数据将为指导未来治疗即预防的实施提供关键数据。
