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针刺疗法治疗神经性耳聋的疗效与安全性:随机对照试验的荟萃分析

Efficacy and safety of acupuncture therapy for nerve deafness: a meta-analysis of randomized controlled trials.

作者信息

Jiang Yuebo, Shi Xian, Tang Yan

机构信息

Department of Internal Medicine Clinical, Acupuncture Division, Chinese PLA General Hospital Beijing, China.

Department of Internal Medicine, Daqing Hospital of Traditional Chinese Medicine Daqing City, Heilongjiang Province, China.

出版信息

Int J Clin Exp Med. 2015 Feb 15;8(2):2614-20. eCollection 2015.

Abstract

BACKGROUND

Acupuncture is one of the important parts of therapeutic methods in traditional Chinese medicine, and has been widely used for the treatment of nerve deafness in recent years. The current study was to evaluate the efficacy and safety of acupuncture therapy for nerve deafness compared with conventional medicine therapy.

METHODS

PubMed, the Chinese National Knowledge Infrastructure Database, the Chinese Science and Technology Periodical Database, the Chinese Biomedical Database, the Wanfang Database were searched for articles published to identify randomized controlled trials evaluating efficacy and side effects between acupuncture and conventional medicine therapies up to 2013/06.

RESULTS

A total of 12 studies, including 527 patients assessed the efficacy and safety of acupuncture therapy for nerve deafness. Overall, the efficacy of acupuncture was significantly better than that of the conventional western medication (RR: 1.54, 95% CI: 1.36-1.74) or traditional Chinese medicines (RR: 1.51, 95% CI: 1.24-1.84), and the efficacy of acupuncture in combination with conventional western medication or traditional Chinese medicine was better than that of the conventional western medication alone (RR: 1.51, 95% CI: 1.29-1.77) or traditional Chinese medicine alone (RR: 1.59, 95% CI: 1.30-1.95). Based on the comparison of number of deafness patients who were completely cured, the efficacy of acupuncture in combination with traditional Chinese medicines was better than that of traditional Chinese medicine alone (RR: 4.62, 95% CI: 1.38-15.47).

CONCLUSIONS

Acupuncture therapy can significantly improve the hearing of patients with nerve deafness, and the efficacy of acupuncture in combination with medication is superior to medication alone.

摘要

背景

针灸是中医治疗方法的重要组成部分,近年来已广泛应用于神经性耳聋的治疗。本研究旨在评估与传统药物治疗相比,针灸治疗神经性耳聋的疗效和安全性。

方法

检索了PubMed、中国知网数据库、维普数据库、中国生物医学数据库、万方数据库,以查找截至2013年6月发表的评估针灸与传统药物治疗疗效和副作用的随机对照试验。

结果

共有12项研究,包括527名患者,评估了针灸治疗神经性耳聋的疗效和安全性。总体而言,针灸的疗效显著优于传统西药(RR:1.54,95%CI:1.36 - 1.74)或中药(RR:1.51,95%CI:1.24 - 1.84),针灸联合传统西药或中药的疗效优于单独使用传统西药(RR:1.51,95%CI:1.29 - 1.77)或单独使用中药(RR:1.59,95%CI:1.30 - 1.95)。基于对完全治愈的耳聋患者数量的比较,针灸联合中药的疗效优于单独使用中药(RR:4.62,95%CI:1.38 - 15.47)。

结论

针灸治疗可显著提高神经性耳聋患者的听力,且针灸联合药物治疗的疗效优于单纯药物治疗。

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