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新疆地区汉族、维吾尔族和哈萨克族急性心肌梗死患者冠心病危险因素及特征分析

Analysis of the risk factors and characteristics of coronary artery disease of Han, Uygur and Kazak patients with acute myocardial infarction in Xinjiang district.

作者信息

Wang Jiao, Liu Zhi-Qiang, He Peng-Yi, Yang Yu-Chun, Zhang Lei

机构信息

Department of Cardiology, First Affiliated Hospital, Xinjiang Medical University China.

出版信息

Int J Clin Exp Med. 2015 Feb 15;8(2):2831-8. eCollection 2015.

Abstract

To discuss the risk factors and characteristics of coronary artery disease of Han, Uygur and Kazak patients with acute myocardial infarction in Xinjiang district. A retrospective analysis of clinical data of 262 cases of Han patients, 166 cases of Uygur patients and 86 cases of Kazak patients was conducted, whose age, body mass index, cholesterol, uric acid, hypertension, type 2 diabetes, smoking, drinking, family history of coronary heart disease, relationship between PCI history and pathogenesis of acute myocardial infarction, and coronary artery disease characteristics were observed and compared in different groups. Between the Han and minority young patients, there were statistically significant differences in the distribution of BMI, lipoprotein a, positive family history of coronary heart disease, uric acid level, the combined aspects of smoking history (P<0.017); there were also statistically significant differences in BMI, TG, HDL-C, apolipoprotein B, positive family history of coronary heart disease distribution between minority young patients and older patients (P<0.017). There were statistically significant differences in the distribution of BMI, TC, HDL-C, LDL-C, apolipoprotein AI, positive family history of coronary heart disease between Han and Uygur patients (P<0.017). Han and Kazak patients had statistically significant differences in the distribution of BMI, TC, LDL-C, apolipoprotein B, lipoprotein a, type 2 diabetes and hypertension (P<0.017). Comparison of patients in Uygur and Kazak showed that there were statistically significant differences in the distribution of BMI, TC, LDL-C, apolipoprotein AI, apolipoprotein B and type 2 diabetes between the two groups (P<0.017). The proportion of zero lesions and single-vessel lesions in minority youth patients was higher than that of elderly patients (P<0.001), and the proportion of two and three lesions was less than that of elderly patients (P<0.001). Gensini score of Han patients was greater than that of Uygur patients (P<0.001) and the Kazak patients (P=0.005); The proportion of Han patients with single-vessel disease was less than that of Kazak patients (P=0.003), and the proportion of patients with double-vessel disease was greater than that of Kazak patients (P=0.007). There were ethnic differences in risk factors and the characteristics of coronary artery disease of AMI patients in Xinjiang district; there were differences between minority youth patients and elderly patients, young patients of Han.

摘要

探讨新疆地区汉族、维吾尔族和哈萨克族急性心肌梗死患者冠心病的危险因素及特点。对262例汉族患者、166例维吾尔族患者和86例哈萨克族患者的临床资料进行回顾性分析,观察并比较不同组患者的年龄、体重指数、胆固醇、尿酸、高血压、2型糖尿病、吸烟、饮酒、冠心病家族史、PCI史与急性心肌梗死发病机制的关系以及冠心病的特点。汉族与少数民族青年患者之间,BMI、脂蛋白a、冠心病家族史阳性、尿酸水平、吸烟史合并情况的分布存在统计学显著差异(P<0.017);少数民族青年患者与老年患者之间,BMI、TG、HDL-C、载脂蛋白B、冠心病家族史阳性分布也存在统计学显著差异(P<0.017)。汉族与维吾尔族患者之间,BMI、TC、HDL-C、LDL-C、载脂蛋白AI、冠心病家族史阳性分布存在统计学显著差异(P<0.017)。汉族与哈萨克族患者之间,BMI、TC、LDL-C、载脂蛋白B、脂蛋白a、2型糖尿病和高血压的分布存在统计学显著差异(P<0.017)。维吾尔族与哈萨克族患者比较显示,两组之间BMI、TC、LDL-C、载脂蛋白AI、载脂蛋白B和2型糖尿病的分布存在统计学显著差异(P<0.017)。少数民族青年患者零病变和单支血管病变的比例高于老年患者(P<0.001),两支和三支病变的比例低于老年患者(P<0.001)。汉族患者的Gensini评分大于维吾尔族患者(P<0.001)和哈萨克族患者(P=0.005);汉族单支血管病变患者的比例低于哈萨克族患者(P=0.003),双支血管病变患者的比例高于哈萨克族患者(P=0.007)。新疆地区AMI患者冠心病的危险因素及特点存在民族差异;少数民族青年患者与老年患者、汉族青年患者之间存在差异。

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