Hoşcan Yeşim, Yiğit Fatma, Müderrisoğlu Haldun
Alanya Training and Research Center, Medicine Faculty of Başkent University Alanya, Turkey.
Adana Training and Research Center, Medicine Faculty of Başkent University Adana, Turkey.
Int J Clin Exp Med. 2015 Feb 15;8(2):2860-6. eCollection 2015.
Mediterranean diet (MD) is considered a model for healthy eating. However, prospective evidence in Turkey evaluating the relationship between MD and cardiovascular events is scarce. We surveyed the adherence of Alanya population to MD and its association with coronary heart diseases (CHD). The study population consisted of participants in Alanya, a region placed southern Turkey. Followed-up 900 participants (52 percent women) initially free of CHD during 5.1 years. The general dietary habits of study population were detected with a food frequency questionnaire. Data obtained from that questionnaire were tested with Mediterranean diet score in order to find out the relevance to Mediterranean diet. A MD score (scale 0-8) was computed reflecting high ratio of monounsaturated to saturated fat; high intake of legumes, cereals, vegetables, and fruits; low intakes of meat and it's products, milk and dairy products. Scoring < 5 was defined as Low-MD consuming, while 5+ as High-MD consuming. We observed 25 incident cases of CHD. Consumption of High-MD was 21% in men and 19% in women. The risk for myocardial infarction, coronary bypass, coronary angioplasty, and any cardiovascular disease in men increased by 1.3 (P = 0.02), 1.4 (P = 0.03), 1.5 (P = 0.01), and 1.3 (P = 0.02), respectively, for each MD score decrease. In women, the risk for myocardial infarction and angioplasty increased by 1.3 (P = 0.02) and 1.5 (P = 0.01), respectively, for each MD score decrease. The risk for coronary bypass, and any cardiovascular disease in women, crude odds ratios ranged from 1.1 to 1.3 but were not statistically significant. The current rate of MD in Alanya is fairly low. There is an inverse association between adherence to MD and the incidence of fatal and non-fatal CHD in initially healthy adults.
地中海饮食(MD)被视为健康饮食的典范。然而,在土耳其,评估MD与心血管事件之间关系的前瞻性证据却很匮乏。我们调查了阿拉尼亚人群对MD的依从性及其与冠心病(CHD)的关联。研究人群包括土耳其南部地区阿拉尼亚的参与者。对900名最初无CHD的参与者进行了5.1年的随访。研究人群的总体饮食习惯通过食物频率问卷进行检测。从该问卷中获得的数据用地中海饮食评分进行测试,以找出与地中海饮食的相关性。计算出一个MD评分(范围为0 - 8),反映单不饱和脂肪与饱和脂肪的高比例;豆类、谷物、蔬菜和水果的高摄入量;肉类及其制品、牛奶和奶制品的低摄入量。评分<5被定义为低MD消费,而5分及以上为高MD消费。我们观察到25例CHD新发病例。男性高MD消费率为21%,女性为19%。男性中,MD评分每降低一分,心肌梗死、冠状动脉搭桥术、冠状动脉血管成形术以及任何心血管疾病的风险分别增加1.3(P = 0.02)、1.4(P = 0.03)、1.5(P = 0.01)和1.3(P = 0.02)。在女性中,MD评分每降低一分,心肌梗死和血管成形术的风险分别增加1.3(P = 0.02)和1.5(P = 0.01)。女性冠状动脉搭桥术和任何心血管疾病的风险,粗略比值比在1.1至1.3之间,但无统计学意义。阿拉尼亚目前的MD率相当低。在最初健康的成年人中,对MD的依从性与致命和非致命CHD的发病率之间存在负相关。