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冠状动脉旁路移植术(CABG)手术候选患者的地中海饮食质量指数和膳食植物化学物质指数

Mediterranean dietary quality index and dietary phytochemical index among patients candidate for coronary artery bypass grafting (CABG) surgery.

作者信息

Farhangi Mahdieh Abbasalizad, Najafi Mahdi, Jafarabadi Mohammad Asghari, Jahangiry Leila

机构信息

Drug Applied Research Center, Nutrition Research Center, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.

Department of Research, Tehran Heart Center, Tehran University of Medical Sciences, North Karegar Street, Tehran, 1411713138, Iran.

出版信息

BMC Cardiovasc Disord. 2017 May 8;17(1):114. doi: 10.1186/s12872-017-0544-z.

Abstract

BACKGROUND

The aim of the present research was to evaluate the relationship between Mediterranean dietary quality index (Med-DQI) and dietary phytochemical index (DPI) with metabolic risk factors of cardiovascular disease in candidates for coronary artery bypass graft (CABG) surgery.

METHODS

This was a cross-sectional study on 454 patients aged 35-80 years as candidates of CABG and hospitalized in Tehran Heart Center. Anthropometric and demographic characteristics were obtained from all participants and a 138-item semi-quantitative food frequency questionnaire (FFQ) was used to evaluate Med-DQI and DPI. Biochemical parameters including HbA1C, serum lipids, albumin, creatinine and C-reactive protein (CRP) were assessed by commercial laboratory methods.

RESULTS

Patients with higher scores of "saturated fatty acids" had lower serum albumin concentrations (P < 0.05). High scores of "cholesterol" subgroup was also accompanied with higher serum Hb A1C percent (P = 0.04). Significantly higher concentrations of serum creatinine were also observed in categorizes with lower "fish" scores. Patients with lower phytochemical intakes had significantly higher Med-DQI scores.

CONCLUSION

According to our findings, high dietary intakes of saturated fatty acids and cholesterol were associated with low serum albumin and Hb A1C concentration. Further studies are needed to better clarify these associations and possible underlying mechanisms.

摘要

背景

本研究旨在评估地中海饮食质量指数(Med-DQI)和膳食植物化学物质指数(DPI)与冠状动脉旁路移植术(CABG)手术候选者心血管疾病代谢危险因素之间的关系。

方法

这是一项针对454名年龄在35 - 80岁的CABG手术候选者且在德黑兰心脏中心住院患者的横断面研究。从所有参与者处获取人体测量和人口统计学特征,并使用一份138项的半定量食物频率问卷(FFQ)来评估Med-DQI和DPI。通过商业实验室方法评估包括糖化血红蛋白(HbA1C)、血脂、白蛋白、肌酐和C反应蛋白(CRP)在内的生化参数。

结果

“饱和脂肪酸”得分较高的患者血清白蛋白浓度较低(P < 0.05)。“胆固醇”亚组得分高也伴随着较高的血清糖化血红蛋白百分比(P = 0.04)。在“鱼类”得分较低的分类中也观察到血清肌酐浓度显著更高。植物化学物质摄入量较低的患者Med-DQI得分显著更高。

结论

根据我们的研究结果,高饱和脂肪酸和胆固醇饮食摄入量与低血清白蛋白和糖化血红蛋白浓度相关。需要进一步研究以更好地阐明这些关联及可能的潜在机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fb2/5422981/01e42d784615/12872_2017_544_Fig1_HTML.jpg

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