Rotellini Matteo, Vezzosi Vania, Bianchi Simonetta
Pathological Anatomy Unit, Department of Surgery and Translational Medicine, University of Florence, L.go Brambilla 3, 50134, Florence, Italy,
Endocr Pathol. 2015 May;26(2):152-6. doi: 10.1007/s12022-015-9372-9.
Epithelioid angiosarcoma of the thyroid is a rare mesenchymal neoplasm, mainly described in the Alpine area. This lesion was initially considered an anaplastic carcinoma, but immunohistochemical and ultrastructural features have proven the endothelial differentiation of tumor cells. In fact, the peculiarity of this tumor concerns the expression of low-molecular weight cytokeratins by neoplastic cells of endothelial origin. We describe a case of epithelioid angiosarcoma of the thyroid occurred in a 73-year-old woman from an Italian non-Alpine area, and a review of non-Alpine primary thyroid epitheliod angiosarcoma is presented.
甲状腺上皮样血管肉瘤是一种罕见的间叶性肿瘤，主要见于阿尔卑斯地区。该病变最初被认为是未分化癌，但免疫组化和超微结构特征证实肿瘤细胞具有内皮分化。事实上，这种肿瘤的独特之处在于内皮起源的肿瘤细胞表达低分子量细胞角蛋白。我们描述了一例发生在一名来自意大利非阿尔卑斯地区的73岁女性的甲状腺上皮样血管肉瘤病例，并对非阿尔卑斯地区原发性甲状腺上皮样血管肉瘤进行了综述。
