Division of Reproductive Endocrinology and Infertility, University of California, San Francisco, California.
Fertil Steril. 2015 Jun;103(6):1379-80. doi: 10.1016/j.fertnstert.2015.04.011. Epub 2015 Apr 30.
Men and women are increasingly delaying childbearing to the late 30s, the 40s and beyond. The implications of this societal change on childhood health and well-being have only recently been a focus of research. There are known increased perinatal risks associated with increasing maternal age, while paternal age seems to have a potentially greater negative impact on childhood health. Understanding the mechanisms underlying the aging of sperm and eggs, and how these changes impact offspring, is a critical next step as we work to help patients build healthy families.
男性和女性越来越多地将生育年龄推迟到 30 多岁、40 多岁甚至更晚。这种社会变化对儿童健康和福祉的影响最近才成为研究的重点。众所周知，随着母亲年龄的增长，围产期风险会增加，而父亲的年龄似乎对儿童健康有更大的潜在负面影响。了解精子和卵子老化的机制，以及这些变化如何影响后代，是我们努力帮助患者建立健康家庭的关键下一步。
