儿科影像、神经认知与遗传学（PING）数据存储库
The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository.
作者信息
Jernigan Terry L, Brown Timothy T, Hagler Donald J, Akshoomoff Natacha, Bartsch Hauke, Newman Erik, Thompson Wesley K, Bloss Cinnamon S, Murray Sarah S, Schork Nicholas, Kennedy David N, Kuperman Joshua M, McCabe Connor, Chung Yoonho, Libiger Ondrej, Maddox Melanie, Casey B J, Chang Linda, Ernst Thomas M, Frazier Jean A, Gruen Jeffrey R, Sowell Elizabeth R, Kenet Tal, Kaufmann Walter E, Mostofsky Stewart, Amaral David G, Dale Anders M
机构信息
Center for Human Development, University of California, San Diego, La Jolla, CA, USA; Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USA; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
Multimodal Imaging Laboratory, University of California, San Diego, La Jolla, CA, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
出版信息
Neuroimage. 2016 Jan 1;124(Pt B):1149-1154. doi: 10.1016/j.neuroimage.2015.04.057. Epub 2015 May 1.
The main objective of the multi-site Pediatric Imaging, Neurocognition, and Genetics (PING) study was to create a large repository of standardized measurements of behavioral and imaging phenotypes accompanied by whole genome genotyping acquired from typically-developing children varying widely in age (3 to 20 years). This cross-sectional study produced sharable data from 1493 children, and these data have been described in several publications focusing on brain and cognitive development. Researchers may gain access to these data by applying for an account on the PING portal and filing a data use agreement. Here we describe the recruiting and screening of the children and give a brief overview of the assessments performed, the imaging methods applied, the genetic data produced, and the numbers of cases for whom different data types are available. We also cite sources of more detailed information about the methods and data. Finally we describe the procedures for accessing the data and for using the PING data exploration portal.
多中心儿科影像、神经认知与遗传学（PING）研究的主要目标是创建一个大型数据库，用于存储行为和影像表型的标准化测量数据，以及从年龄跨度较大（3至20岁）的正常发育儿童中获取的全基因组基因分型数据。这项横断面研究产生了来自1493名儿童的可共享数据，这些数据已在多篇关注大脑和认知发育的出版物中有所描述。研究人员可以通过在PING门户网站上申请账户并提交数据使用协议来获取这些数据。在此，我们描述了儿童的招募和筛选过程，并简要概述了所进行的评估、应用的成像方法、产生的基因数据，以及可获得不同数据类型的病例数量。我们还引用了有关方法和数据的更详细信息的来源。最后，我们描述了访问数据和使用PING数据探索门户网站的程序。
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