Winhusen Theresa M, Somoza Eugene C, Lewis Daniel F, Kropp Frankie, Theobald Jeff, Elkashef Ahmed
Addiction Sciences Division, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH 45229, USA.
Addiction Sciences Division, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH 45229, USA ; Veterans Affairs Medical Center (VISN 10), 3200 Vine Street, Cincinnati, OH 45220, USA.
ISRN Addict. 2014 Mar 4;2014:912863. doi: 10.1155/2014/912863. eCollection 2014.
Background. There is a strong association between crack/cocaine use and increased sexual risk behavior, but little research on the efficacy of HIV education for decreasing such behavior in crack/cocaine-addicted individuals in substance abuse treatment. Method. Datasets from two cocaine dependence trials including either one or three HIV education sessions, respectively, were analyzed for changes over time in the proportion of participants practicing safe sex. A pooled dataset from two earlier trials not offering HIV education was also analyzed. Results. We included 83 participants from the 1-session trial and 65 participants from the 3-session trial. Both sets of participants evidenced a significant increase in the proportion of participants having safe sex with casual partners. Participants in the 3-session HIV education study also evidenced a significant increase in the proportion of participants having safe sex with regular partners. In the trials without HIV education, no change in safe sex practices was found, and change in condom use was observed only among female participants. Conclusions. These findings are consistent with recommendations that HIV education/counseling should be provided to individuals in substance abuse treatment. A randomized controlled trial to confirm these results may be warranted. This trial is registered with NCT00033033, NCT00086255, NCT00015106, and NCT00015132.
背景。吸食快克/可卡因与性风险行为增加之间存在紧密关联，但针对在药物滥用治疗中接受快克/可卡因成瘾治疗的个体开展的艾滋病毒教育在减少此类行为方面的效果研究甚少。方法。分别对两项可卡因依赖试验（一项包含一次艾滋病毒教育课程，另一项包含三次艾滋病毒教育课程）的数据集中参与者进行安全性行为的比例随时间的变化情况进行分析。还对两项早期未提供艾滋病毒教育的试验的汇总数据集进行了分析。结果。我们纳入了单次课程试验的83名参与者和三次课程试验的65名参与者。两组参与者与临时性伴侣进行安全性行为的比例均显著增加。三次课程艾滋病毒教育研究中的参与者与固定性伴侣进行安全性行为的比例也显著增加。在未开展艾滋病毒教育的试验中，安全性行为习惯未发生变化，仅在女性参与者中观察到避孕套使用情况有所改变。结论。这些研究结果与向接受药物滥用治疗的个体提供艾滋病毒教育/咨询的建议一致。可能有必要开展一项随机对照试验来证实这些结果。该试验已在NCT00033033、NCT00086255、NCT00015106和NCT00015132注册。
