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从一名急性Q热患者中分离出对小鼠毒力较低的伯纳特柯克斯体菌株。

Isolation of a Coxiella burnetii strain that has low virulence for mice from a patient with acute Q fever.

作者信息

Oda H, Yoshiie K

机构信息

Department of Bacteriology, Faculty of Medicine, Kagoshima University.

出版信息

Microbiol Immunol. 1989;33(11):969-73. doi: 10.1111/j.1348-0421.1989.tb00984.x.

DOI:10.1111/j.1348-0421.1989.tb00984.x
PMID:2593878
Abstract

Coxiella burnetii was isolated from a patient with Q fever. It could not be determined whether this was an imported case or an indigenous one. Identification of the isolate was made by electron microscopic morphology and the indirect fluorescent antibody test with convalescent-phase serum from a Q fever patient having a known titer of antibody to C. burnetii. The isolated strain, named TK-1, caused no symptoms in ddY and BALB/c mice except when the mice were treated with cyclophosphamide.

摘要

从一名患Q热的患者身上分离出了伯氏考克斯体。无法确定这是一例输入性病例还是本地病例。通过电子显微镜形态学以及使用来自一名已知伯氏考克斯体抗体滴度的Q热患者的恢复期血清进行间接荧光抗体试验对分离株进行鉴定。分离出的菌株命名为TK-1,除了用环磷酰胺处理的ddY和BALB/c小鼠外,在其他小鼠身上未引起任何症状。

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