Steinl David C, Kaufmann Beat A
Department of Biomedicine, University Hospital Basel, Hebelstrasse 20, Basel 4031, Switzerland.
Division of Cardiology, University Hospital Basel, Petersgraben 4, Basel 4031, Switzerland.
Int J Mol Sci. 2015 Apr 29;16(5):9749-69. doi: 10.3390/ijms16059749.
Atherosclerosis and its consequences like acute myocardial infarction or stroke are highly prevalent in western countries, and the incidence of atherosclerosis is rapidly rising in developing countries. Atherosclerosis is a disease that progresses silently over several decades before it results in the aforementioned clinical consequences. Therefore, there is a clinical need for imaging methods to detect the early stages of atherosclerosis and to better risk stratify patients. In this review, we will discuss how ultrasound imaging can contribute to the detection and risk stratification of atherosclerosis by (a) detecting advanced and early plaques; (b) evaluating the biomechanical consequences of atherosclerosis in the vessel wall;
动脉粥样硬化及其后果，如急性心肌梗死或中风，在西方国家极为普遍，且在发展中国家，动脉粥样硬化的发病率正在迅速上升。动脉粥样硬化是一种在导致上述临床后果之前会在数十年间悄然发展的疾病。因此，临床上需要成像方法来检测动脉粥样硬化的早期阶段，并更好地对患者进行风险分层。在本综述中，我们将讨论超声成像如何通过以下方式有助于动脉粥样硬化的检测和风险分层：（a）检测进展期和早期斑块；（b）评估动脉粥样硬化对血管壁的生物力学影响。
