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微量元素为动脉粥样硬化的诊断开辟了新方向。

Trace Elements Open a New Direction for the Diagnosis of Atherosclerosis.

作者信息

Meng Heyu, Ruan Jianjun, Chen Yanqiu, Yan Zhaohan, Liu Jinsha, Wang Xue, Meng Xin, Wang Jingru, Zhang Qiang, Li Xiangdong, Meng Fanbo

机构信息

Department of Cardiology, China-Japan Union Hospital of Jilin University, 130033 Changchun, Jilin, China.

Jilin Provincial Precision Medicine Key Laboratory for Cardiovascular Genetic Diagnosis, Jilin Provincial Cardiovascular Research Institute, Jilin University, 130033 Changchun, Jilin, China.

出版信息

Rev Cardiovasc Med. 2023 Jan 11;24(1):23. doi: 10.31083/j.rcm2401023. eCollection 2023 Jan.

DOI:10.31083/j.rcm2401023
PMID:39076854
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11270404/
Abstract

Abnormal or excessive accumulation of adipose tissue leads to a condition called obesity. Long-term positive energy balance arises when energy intake surpasses energy expenditure, which increases the risk of metabolic and other chronic diseases, such as atherosclerosis. In industrialized countries, the prevalence of coronary heart disease is positively correlated with the human development index. Atherosclerotic cardiovascular disease (ACD) is among the primary causes of death on a global scale. There is evidence to support the notion that individuals from varied socioeconomic origins may experience varying mortality effects as a result of high blood pressure, high blood sugar, raised cholesterol levels, and high body mass index (BMI). However, it is believed that changes in the concentration of trace elements in the human body are the main contributors to the development of some diseases and the transition from a healthy to a diseased state. Metal trace elements, non-metal trace elements, and the sampling site will be examined to determine whether trace elements can aid in the diagnosis of atherosclerosis. This article will discuss whether trace elements, discussed under three sections of metal trace elements, non-metal trace elements, and the sampling site, can participate in the diagnosis of atherosclerosis.

摘要

脂肪组织异常或过度积累会导致一种称为肥胖症的状况。当能量摄入超过能量消耗时,就会出现长期的正能量平衡,这会增加患代谢性疾病和其他慢性疾病的风险,如动脉粥样硬化。在工业化国家,冠心病的患病率与人类发展指数呈正相关。动脉粥样硬化性心血管疾病(ACD)是全球主要死因之一。有证据支持这样一种观点,即来自不同社会经济背景的个体可能会因高血压、高血糖、胆固醇水平升高和高体重指数(BMI)而经历不同的死亡影响。然而,人们认为人体中微量元素浓度的变化是某些疾病发展以及从健康状态转变为患病状态的主要因素。将对金属微量元素、非金属微量元素和采样部位进行检测,以确定微量元素是否有助于动脉粥样硬化的诊断。本文将讨论在金属微量元素、非金属微量元素和采样部位三个部分下讨论的微量元素是否能够参与动脉粥样硬化的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00d/11270404/b6dccf3bf83f/2153-8174-24-1-023-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00d/11270404/563fae68f9cc/2153-8174-24-1-023-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00d/11270404/b6dccf3bf83f/2153-8174-24-1-023-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00d/11270404/563fae68f9cc/2153-8174-24-1-023-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00d/11270404/b6dccf3bf83f/2153-8174-24-1-023-g2.jpg

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