Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Small. 2015 Aug;11(31):3768-71. doi: 10.1002/smll.201500240. Epub 2015 May 4.
Following the principle of frame-guided assembly (FGA), a small amphiphilic molecule, sodium dodecyl sulfate, is shown to form vesicles with cholesterol as the leading hydrophobic group. These findings not only demonstrate the generality of the FGA but also provide a clue to understand the formation mechanism of the cell membrane, and even the origin of life.
根据框架引导组装（FGA）原理，一种小分子两亲性分子十二烷基硫酸钠与胆固醇作为主导疏水区形成囊泡。这些发现不仅证明了 FGA 的普遍性，也为理解细胞膜的形成机制，甚至生命的起源提供了线索。
