Zhu Weiwei, Chai Xiaoyun, Wang Baogang, Zou Yan, Wang Ting, Meng Qingguo, Wu Qiuye
College of Pharmacy, Yantai University, Yantai, Shandong 264005, China.
Chem Commun (Camb). 2015 Jun 14;51(47):9608-11. doi: 10.1039/c5cc02496j.
A cyclic boronate structure was incorporated into Si-rhodamine to design a pH-activatable near-infrared (NIR) probe based on the reversible ring-opening process triggered by H(+). The probe showed general suitability of specific labelling of acidic lysosomes and tracking their pH changes in living cells.
将环状硼酸酯结构引入硅罗丹明中，基于氢离子引发的可逆开环过程设计了一种pH可激活的近红外（NIR）探针。该探针显示出对酸性溶酶体进行特异性标记并追踪其在活细胞中pH变化的普遍适用性。
