Hoddy Kristin K, Kroeger Cynthia M, Trepanowski John F, Barnosky Adrienne R, Bhutani Surabhi, Varady Krista A
Department of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 West Taylor Street, Room 506 F, Chicago, IL, 60612, USA.
Nutr J. 2015 May 6;14:44. doi: 10.1186/s12937-015-0029-9.
Alternate day fasting (ADF; ad libitum intake "feed day" alternated with 75% restriction "fast day"), is effective for weight loss, but the safety of the diet has been questioned. Accordingly, this study examined occurrences of adverse events and eating disorder symptoms during ADF.
Obese subjects (n = 59) participated in an 8-week ADF protocol where food was provided on the fast day. Body weight decreased (P < 0.0001) by 4.2 ± 0.3%. Some subjects reported constipation (17%), water retention (2%), dizziness (<20%), and general weakness (<15%). Bad breath doubled from baseline (14%) to post-treatment (29%), though not significantly. Depression and binge eating decreased (P < 0.01) with ADF. Purgative behavior and fear of fatness remained unchanged. ADF helped subjects increase (P < 0.01) restrictive eating and improve (P < 0.01) body image perception.
Therefore, ADF produces minimal adverse outcomes, and has either benign or beneficial effects on eating disorder symptoms.
隔日禁食(ADF;即随意进食的“进食日”与75%热量限制的“禁食日”交替进行)对体重减轻有效,但该饮食方式的安全性受到质疑。因此,本研究调查了隔日禁食期间不良事件和饮食失调症状的发生情况。
肥胖受试者(n = 59)参与了一项为期8周的隔日禁食方案,禁食日提供食物。体重下降了4.2±0.3%(P < 0.0001)。一些受试者报告有便秘(17%)、水潴留(2%)、头晕(<20%)和全身无力(<15%)。口臭从基线时的14%增加了一倍,至治疗后为29%,但差异无统计学意义。抑郁和暴饮暴食随着隔日禁食而减少(P < 0.01)。催泻行为和对肥胖的恐惧保持不变。隔日禁食有助于受试者增加限制饮食(P < 0.01)并改善身体意象感知(P < 0.01)。
因此,隔日禁食产生的不良后果极小,并且对饮食失调症状具有良性或有益影响。