Zalavras Athanasios, Fatouros Ioannis G, Deli Chariklia K, Draganidis Dimitris, Theodorou Anastasios A, Soulas Dimitrios, Koutsioras Yiannis, Koutedakis Yiannis, Jamurtas Athanasios Z
Department of Physical Education & Sport Science, University of Thessaly, Karies, 42100 Trikala, Greece.
Department of Physical Education & Sport Science, University of Thrace, 69100 Komotini, Greece ; Department of Kinesiology, Institute for Research & Technology, Thessaly, 42100 Trikala, Greece.
Oxid Med Cell Longev. 2015;2015:283921. doi: 10.1155/2015/283921. Epub 2015 Apr 6.
Redox status changes during an annual training cycle in young and adult track and field athletes and possible differences between the two age groups were assessed. Forty-six individuals (24 children and 22 adults) were assigned to four groups: trained adolescents, (TAD, N = 13), untrained adolescents (UAD, N = 11), trained adults (TA, N = 12), and untrained adults (UA, N = 10). Aerobic capacity and redox status related variables [total antioxidant capacity (TAC), glutathione (GSH), catalase activity, TBARS, protein carbonyls (PC), uric acid, and bilirubin] were assessed at rest and in response to a time-trial bout before training, at mid- and posttraining. TAC, catalase activity, TBARS, PC, uric acid, and bilirubin increased and GSH declined in all groups in response to acute exercise independent of training status and age. Training improved aerobic capacity, TAC, and GSH at rest and in response to exercise. Age affected basal and exercise-induced responses since adults demonstrated a greater TAC and GSH levels at rest and a greater rise of TBARS, protein carbonyls, and TAC and decline of GSH in response to exercise. Catalase activity, uric acid, and bilirubin responses were comparable among groups. These results suggest that acute exercise, age, and training modulate the antioxidant reserves of the body.
评估了年轻和成年田径运动员在年度训练周期中的氧化还原状态变化以及两个年龄组之间可能存在的差异。46名个体（24名儿童和22名成年人）被分为四组：训练过的青少年（TAD，N = 13）、未训练的青少年（UAD，N = 11）、训练过的成年人（TA，N = 12）和未训练的成年人（UA，N = 10）。在休息时以及训练前、训练中期和训练后的计时赛期间，评估了有氧能力和与氧化还原状态相关的变量[总抗氧化能力（TAC）、谷胱甘肽（GSH）、过氧化氢酶活性、硫代巴比妥酸反应物（TBARS）、蛋白质羰基（PC）、尿酸和胆红素]。无论训练状态和年龄如何，所有组在急性运动后，TAC、过氧化氢酶活性、TBARS、PC、尿酸和胆红素均升高，而GSH下降。训练改善了休息时以及运动后的有氧能力、TAC和GSH。年龄影响基础和运动诱导的反应，因为成年人在休息时表现出更高的TAC和GSH水平，并且在运动后TBARS、蛋白质羰基以及TAC的升高幅度更大，GSH下降幅度更大。各组之间过氧化氢酶活性、尿酸和胆红素的反应相当。这些结果表明，急性运动、年龄和训练会调节身体的抗氧化储备。
