Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zürich, University of Zürich, Raemistrasse 100, Zurich, CH-8091 Switzerland.
Antimicrob Resist Infect Control. 2015 May 6;4:18. doi: 10.1186/s13756-015-0052-9. eCollection 2015.
Optimizing user satisfaction with alcohol-based hand rubs (ABHR) may be vital to enhance hand hygiene performance. This study tested the tolerability and acceptability of a new ABHR (EVO9; Ecolab) in healthcare workers under daily working conditions and evaluated the practicability of the corresponding WHO protocol.
We strictly applied the WHO single product ABHR evaluation protocol. A trained observer assessed hand skin conditions of healthy volunteers using at least 30 ml ABHR per day during their clinical work at baseline, day 3-5 and one month (visit 1-3). Participants rated ABHR tolerability and acceptability at visit 2 and 3. Additionally, we registered study time for participants and study team.
Among 46 volunteers, 76% were female; 37% nurses, 28% physicians. Skin was observer-rated "not" or "incidentally" dry in 64.4%, 77.8%, and 90.9% participants at visit 1, 2, and 3, respectively. EVO9 was scored ≥5 (progressive scale, 1-7) for appearance, intactness, moisture content, and sensation by 95.7%, 97.7%, 88.9%, and 97.8% participants at visit 3, respectively. All WHO benchmarks were exceeded except for "speed of drying" at visit 2, and "texture" at visit 2 and 3. Cumulative study time expenditure was 14 days for the observer and four days for participants.
EVO9 was well tolerated and accepted according to the WHO single ABHR evaluation protocol with the potential for improvement for stickiness. The WHO protocol is feasible but requires considerable time and logistics. It does not preclude bias, in this case especially due to the necessary switch to personal dispensers.
优化酒精基手部消毒剂（ABHR）的用户满意度对于提高手部卫生性能可能至关重要。本研究在日常工作条件下测试了一种新型 ABHR（EVO9；艺康）在医护人员中的耐受性和可接受性，并评估了相应的世卫组织方案的实用性。
我们严格应用世卫组织单一产品 ABHR 评估方案。一名经过培训的观察员在健康志愿者的临床工作期间，每天至少使用 30 毫升 ABHR，在基线、第 3-5 天和一个月（第 1-3 次就诊）评估手部皮肤状况。参与者在第 2 次和第 3 次就诊时评价 ABHR 的耐受性和可接受性。此外，我们还记录了参与者和研究团队的研究时间。
在 46 名志愿者中，76%为女性；37%为护士，28%为医生。在第 1、2 和 3 次就诊时，分别有 64.4%、77.8%和 90.9%的参与者的皮肤被观察者评为“不”或“偶然”干燥。在第 3 次就诊时，分别有 95.7%、97.7%、88.9%和 97.8%的参与者对外观、完整性、水分含量和感觉的评分≥5（递增量表，1-7）。除了第 2 次就诊时的“干燥速度”和第 2 次和第 3 次就诊时的“质地”外，所有世卫组织基准均得到超过。观察者的累计研究时间为 14 天，参与者的累计研究时间为 4 天。
根据世卫组织单一 ABHR 评估方案，EVO9 具有良好的耐受性和可接受性，可能需要改进粘性。世卫组织方案是可行的，但需要相当多的时间和后勤。它不能排除偏见，在这种情况下，特别是由于必须切换到个人分配器。
